Group 6A Drug Profiles

Question 1

Etomidate Class

Answer 1

Non-Barbiturate Hypnotic
Anestesia inducing agent

Question 2

Etomidate MOA

Answer 2

Ultra-short acting hypnotic that produces rapid sedation with minimal respiratory and cardiovascular depression.

Question 3

Etomidate Indication

Answer 3

• Pre-paralytic sedation for medication facilitated sedation.

Question 4

Etomidate Adult Dose and Route

Answer 4

• Procedural Sedation
• 0.2-0.4 mg/kg IV/IO over 30-60 secs. (Typical adult dose is 20mg)

Question 5

Etomidate Onset of Action

Answer 5

30-60 secs

Question 6

Etomidate Peak Effect

Answer 6

1 min.

Question 7

Etomidate Duration of Action

Answer 7

5-10 min.

Question 8

Ketamine Class

Answer 8

• Analgesic (Schedule lll drug)
• General and dissociative anesthesic

Question 9

Ketamine Class

Answer 9

• Analgesic (Schedule lll drug)
• General and dissociative anesthesic

Question 10

Ketamine MOA

Answer 10

-Blocks pain receptors and minimizes spinal cord activity
- Effects brains association pathways between thalamus and limbic system

Question 11

Ketamine Indications

Answer 11

• Procedural Sedation
• Management of agitated or violent behavior
• Pain control

Question 12

Ketamine Adult Dose and Route (all doses are for patients 15 yrs and older)
Procedural Sedation

Answer 12

• 2mg/kg IV/IO over 1-2 min.

Question 13

Ketamine Adult Dose and Route (all doses are for patients 15 yrs and older)
Pain control

Answer 13

• Moderate Pain: 0.5 mg/kg IN (max single dose 50mg; max total dose 100mg)
• Severe Pain: 0.25 mg/kg IV/IO/IM (max single dose 25mg; max total dose 100 mg)

Question 14

Ketamine Adult Dose and Route (all doses are for patients 15 yrs and older)
Chemical Restraint

Answer 14

1 mg/kg IV or 3 mg/kg IM

Question 15

Ketamine Onset of Action

Answer 15

30 sec

Question 16

Ketamine Peak Effect

Answer 16

30 sec to 5 min.

Question 17

Ketamine Duration of Action

Answer 17

10-15 min.

Question 18

Succinylcholine Class

Answer 18

• Depolarizing neuromuscular blocker
• skeletal muscle relaxant

Question 19

Succinylcholine MOA

Answer 19

• ultra-short acting skeletal muscle relaxant that mimics acetylcholine
• Binds with cholinergic receptors on motor endplate, producing phase 1 block manifested by muscle fasciculations.

Question 20

Succinylcholine Indications

Answer 20

Adjunct to provide skeletal muscle relaxation and facilitate tracheal intubation and ventilation

Question 21

Succinylcholine Adult Dose and route

Answer 21

• Paralytic to facilitate tracheal intubation
• 1-1.5 mg/kg IV/IO rapid push

Question 22

Succinylcholine Onset of Action

Answer 22

45-60 sec

Question 23

Succinylcholine Peak Effect

Answer 23

1-3 min

Question 24

Succinylcholine Duration of Action

Answer 24

4-6 min

Question 25

Fentanyl Class

Answer 25

Synthetic opioid analgesic (schedule ll drug)

Question 26

Fentanyl MOA

Answer 26

Binds to opioid receptors, producing analgesia, euphoria, respiratory depression, and sedation

Question 27

Fentanyl MOA

Answer 27

Binds to opioid receptors, producing analgesia, euphoria, respiratory depression, and sedation

Question 28

Fentanyl Indications

Answer 28

- Pain management - Anesthetic drug - Severe respiratory distress (palliative care)

Question 29

Fentanyl Indications

Answer 29

- Pain management - Anesthetic drug - Severe respiratory distress (palliative care)

Question 30

Fentanyl Adult Dose and Route Discomfort

Answer 30

- Moderate discomfort * 1mg/kg IM/IN (max initial dose 100 mg; max total dose 200mg) - Severe discomfort * 1mg/kg IV/IO (max initial dose 100 mg; max total dose 200mg)

Question 31

Fentanyl Adult Dose and Route Discomfort

Answer 31

- Moderate discomfort * 1mg/kg IM/IN (max initial dose 100 mg; max total dose 200mg) - Severe discomfort * 1mg/kg IV/IO (max initial dose 100 mg; max total dose 200mg)

Question 32

Fentanyl Adult Dose and Route Palliative care (Severe Respiratory Distress)

Answer 32

- 25mg in 2mL NS via SVN

Question 33

Fentanyl Onset of Action

Answer 33

Immediate

Question 34

Fentanyl Peak Effect

Answer 34

3-5 min

Question 35

Fentanyl Peak Effect

Answer 35

3-5 min

Question 36

Fentanyl Duration of Action

Answer 36

30 to 60 min