Group 6A Drug Profiles Flashcards

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1
Q

Etomidate Class

A

Non-Barbiturate Hypnotic
Anestesia inducing agent

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2
Q

Etomidate MOA

A

Ultra-short acting hypnotic that produces rapid sedation with minimal respiratory and cardiovascular depression.

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3
Q

Etomidate Indication

A
  • Pre-paralytic sedation for medication facilitated sedation.
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4
Q

Etomidate Adult Dose and Route

A
  • Procedural Sedation
  • 0.2-0.4 mg/kg IV/IO over 30-60 secs. (Typical adult dose is 20mg)
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5
Q

Etomidate Onset of Action

A

30-60 secs

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6
Q

Etomidate Peak Effect

A

1 min.

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7
Q

Etomidate Duration of Action

A

5-10 min.

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8
Q

Ketamine Class

A
  • Analgesic (Schedule lll drug)
  • General and dissociative anesthesic
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9
Q

Ketamine Class

A
  • Analgesic (Schedule lll drug)
  • General and dissociative anesthesic
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10
Q

Ketamine MOA

A

-Blocks pain receptors and minimizes spinal cord activity
- Effects brains association pathways between thalamus and limbic system

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11
Q

Ketamine Indications

A
  • Procedural Sedation
  • Management of agitated or violent behavior
  • Pain control
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12
Q

Ketamine Adult Dose and Route (all doses are for patients 15 yrs and older)
Procedural Sedation

A
  • 2mg/kg IV/IO over 1-2 min.
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13
Q

Ketamine Adult Dose and Route (all doses are for patients 15 yrs and older)
Pain control

A
  • Moderate Pain: 0.5 mg/kg IN (max single dose 50mg; max total dose 100mg)
  • Severe Pain: 0.25 mg/kg IV/IO/IM (max single dose 25mg; max total dose 100 mg)
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14
Q

Ketamine Adult Dose and Route (all doses are for patients 15 yrs and older)
Chemical Restraint

A

1 mg/kg IV or 3 mg/kg IM

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15
Q

Ketamine Onset of Action

A

30 sec

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16
Q

Ketamine Peak Effect

A

30 sec to 5 min.

17
Q

Ketamine Duration of Action

A

10-15 min.

18
Q

Succinylcholine Class

A
  • Depolarizing neuromuscular blocker
  • skeletal muscle relaxant
19
Q

Succinylcholine MOA

A
  • ultra-short acting skeletal muscle relaxant that mimics acetylcholine
  • Binds with cholinergic receptors on motor endplate, producing phase 1 block manifested by muscle fasciculations.
20
Q

Succinylcholine Indications

A

Adjunct to provide skeletal muscle relaxation and facilitate tracheal intubation and ventilation

21
Q

Succinylcholine Adult Dose and route

A
  • Paralytic to facilitate tracheal intubation
  • 1-1.5 mg/kg IV/IO rapid push
22
Q

Succinylcholine Onset of Action

A

45-60 sec

23
Q

Succinylcholine Peak Effect

A

1-3 min

24
Q

Succinylcholine Duration of Action

A

4-6 min

25
Q

Fentanyl Class

A

Synthetic opioid analgesic (schedule ll drug)

26
Q

Fentanyl MOA

A

Binds to opioid receptors, producing analgesia, euphoria, respiratory depression, and sedation

27
Q

Fentanyl MOA

A

Binds to opioid receptors, producing analgesia, euphoria, respiratory depression, and sedation

28
Q

Fentanyl Indications

A
  • Pain management
  • Anesthetic drug
  • Severe respiratory distress (palliative care)
29
Q

Fentanyl Indications

A
  • Pain management
  • Anesthetic drug
  • Severe respiratory distress (palliative care)
30
Q

Fentanyl Adult Dose and Route
Discomfort

A
  • Moderate discomfort
  • 1mg/kg IM/IN (max initial dose 100 mg; max total dose 200mg)
  • Severe discomfort
  • 1mg/kg IV/IO (max initial dose 100 mg; max total dose 200mg)
31
Q

Fentanyl Adult Dose and Route
Discomfort

A
  • Moderate discomfort
  • 1mg/kg IM/IN (max initial dose 100 mg; max total dose 200mg)
  • Severe discomfort
  • 1mg/kg IV/IO (max initial dose 100 mg; max total dose 200mg)
32
Q

Fentanyl Adult Dose and Route
Palliative care (Severe Respiratory Distress)

A
  • 25mg in 2mL NS via SVN
33
Q

Fentanyl Onset of Action

A

Immediate

34
Q

Fentanyl Peak Effect

A

3-5 min

35
Q

Fentanyl Peak Effect

A

3-5 min

36
Q

Fentanyl Duration of Action

A

30 to 60 min