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AUBF 2 CSF (Finals) > Gross Analysis > Flashcards

Gross Analysis Flashcards

1
Q

normal csf volume for:
adults
neonates

A

a: 90-150mL
n: 10-60 mL

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2
Q

normal csf appearance

A

crystal clear

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3
Q

what can be seen in hazy/ turbid/ milky/ cloudy csf sample?

A

> 20/uL WBCs
400/uL RBCs
Microorganisms
Proteins
Lipids

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4
Q

hazy/ turbid/ milky/ cloudy csf sample can be noted in what condition?

A

infection and meningitis

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5
Q

abnormal discoloration of csf

A

XANTHOCHROMIA

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6
Q

main reason of xanthochromia

A

presence of RBC degradation products

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7
Q

in xanthochromia, pink sample has slight amount of _

A

oxyhemoglobin

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8
Q

in xanthochromia, what color of sample has heavy hemolysis?

A

orange

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9
Q

in xanthochromia, yellow discoloration happens due to conversion of oxyhemoglobin to _?

A

bilirubin

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10
Q

presence of bilirubin in csf is termed

A

BILIRACHIA

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11
Q

xanthochromia can also be seen in the presence / increased of?

A

protein (>150mg/dL) = damage in BBB
melanin = meningeal melanosarcoma
karotene = hypervitaninosis A
anti-TB drugs (rifampicin)
anti-septic contamination (iodine)

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12
Q

increased protein in csf can result to what color of discoloration?

A

yellowish due to damage in BBB

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13
Q

presence of melanin in csf can result to what color of discoloration?

A

brownish due to meningeal melanosarcoma

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14
Q

presence of karotene in csf can result to what color of discoloration?

A

orange due to hypervitaminosis A

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15
Q

vitamin A precursor

A

karotene

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16
Q

rifampicin can result to what color of csf discoloration?

A

red orange

17
Q

iodine can result to what color of csf discoloration?

A

yellowish

18
Q

bloody csf has _ amount of RBC

A

> 600/uL

19
Q

two reasons for bloody csf

A
  • traumatic tap
  • intracranial hemorrhage
20
Q

distribution of blood in:
traumatic tap
intracranial hemorrhage

A

TT: UNEVEN 1>2>3
IH: EVEN 1=2=3

21
Q

clot formation in bloody csf is possible to?

A

traumatic tap

22
Q

supernatant appearance of TT & IH

A

tt: clear
ih: xanthochromic

23
Q

intracranial hemorrhage is positive in :

A

Erythrophages (Hemosiderin, Hematoidin crystals)
D-dimer

24
Q

oily csf can be seen in

A

radiographic contrast media

25
Q

in meningitis, froin syndrome, blockage of csf circulation, and traumatic tap has _ csf

A

clotted

26
Q

froin syndrome has combination of

A

Xanthochromia,↑ protein, and hypercoagulability

27
Q

can be seen in tubercular meningitis and if sample is refrigerated overnight

A

pellicle (web-like)

28
Q

viscosity of normal csf

A

water-like

29
Q

viscous csf can be seen in

A

Metastatic mucin-producing adenocarcinoma

Cryptococcal meningitis (Polysaccharide capsule contributes to the viscosity)

Liquid Nucleus Pulposus

AUBF 2 CSF (Finals) (3 decks)

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