Granuloma

Question 1

What is peripheral giant cell granuloma and how does it present?

Answer 1

Reactive hyperplastic lesion
- Soft tissue purple/blueish/reddish nodule
- contains large multinucleated giant cells

Question 2

Cause of PGCG?

Answer 2

Thought to be local irritation
- plaque
- overhanging restorations
- trauma

Question 3

Aetiology of PGCG?

Answer 3

Mandible >

Women >

30-40>

Question 4

What is oral Pyogenic granuloma?

Answer 4

Soft and often painless mass in oral cavity
- deep red to purple colour
- non lobulated mass of angiomatous tissue
- capillary proliferation

Question 5

Tx pyogenic granuloma?

Answer 5

Surgical excision
- debridement of underlying tissue with 2mm margins
- any foreign body, calculus or defective restorations removed too

Question 6

What is central giant cell granuloma?

Answer 6

Benign aggressive osteolytic neoplasm of maxfacial region
- multinucleated giant cells

CGCG = within jaw bone

PGCG = not in jaw bone

Question 7

Histology pyogenic granuloma?

Answer 7

Multinucleated giant cells
- background of plump ovoid and spindle shaped mesenchymal cells

Question 8

Aetiology CGCG

Answer 8

Mandible >
- body anterior to first molars

Age < 30

Female >

Can be consequence of parathyroid tumour

Question 9

Clinical presentation of CGCG?

Answer 9

Asymptomatic

Or

Rapid hollowing of bone
- cortical expansion
- root resorption
- displacement of adjacent tissues
- pain