Gram Positive Bacteria (Cocci) Flashcards
S.Saprophyticus, S.Epidermis - Coagulase Negative Staphylococcus
- Skin commensal
- Device associated infections including prosthetic valve endocarditis
- Rx - 50% flucloxacillin resistant
- Regimen depends on sensitivities
- Combinations including rifampicin often used for device associated infections.
- S.saprophyticus - cause of UTIs in young women
- Rx - flucloxacillin or nitrofurantoin
S.Aureus - Coagulase Positive Staphyloccus
- Skin and soft tissue infections
- Endocarditis
- Toxin-mediated diseases
- Meticillin sensitive S.aureus –> Rx - flucloxacillin or erythromycin
- Meticillin resistant S.aureus (MRSA) –> Rx - vancomycin or linezolid
Streptococcus Pneumoniae = Optochin susceptible, Alpha-haemolytic streptococci
- Draughtsmen colonies
- Pharyngeal commensal
- Community acquired pneumonia
- Meningitis
- Vaccines available
- Rx - benzylpenicillin (IV) or amoxicillin (PO)
- Penicillin resistant
Viridans Streptococci (species) = Optochin susceptible, Alpha-haemolytic streptococci
- Pharyngeal comsmensals
- Includes: S.mitis, S.oralis, S.salivarius, S.mutans
- Native valve endocarditis
- Rx - benzylpenicillin (IV) and synergistic gentamicin
*Streptococcus pyogenes - *Group A Beta-haemolytic Streptococci
- Pharyngitis
- Skin and soft tissue infections incuding necrotising fascitis
- Rheumatic fever/ scarlet fever
- Puerperal sepsis
- ASOT/ DNAse B
- Rx - benzylpenicillin (IV) or amoxicillin (PO)
*Streptococcus agalactiae - *Group B Beta-haemolytic Streptococci
- Commensal of female GU tract
- UTIs
- Neonatal sepsis and meningitis
- Endocarditis
- Septic arthritis
- Rx - benzylpenicillin (IV) plus gentamycin (severe) or amoxicillin (PO)
*S.equi, S.equisimilus, S.zooepiodemicus - *Group C Beta-haemolytic streptococci
- Pharyngitis
- Skin and soft tissue infections
- Rx - benzylpenicillin (IV) or amoxicillin (PO)
Enterococcus species - Group D Beta-haemolytic streptococci (also often non-haemolytic)
- Commensals of GI and GU
- UTIs
- Endocarditis
- Polymicrobial infections from GI perforation
- Cephalosporin resistant
- Rx - amoxicillin *(E.faecalis) *or vancomycin (E.faecium)
- Vancomycin resistant enterococci (VRE)
*S.bovis - *Group D Beta-haemolytic streptococci
- Endocarditis
- Association with colon cancer
- Rx - benzylpenicillin (IV) or amoxicillin (PO)
*S.anginosus, S.constellatus, S.intermedius - *Group F Beta-haemolytic Streptococci
- ‘Milleri group’
- Intra-abdominal abscesses, often polymicrobial
- Rx - benzylpenicillin (IV) or amoxicillin (PO)
S.dysgalactiae - Group G Beta-haemolytic streptococci
- Skin and soft tissue infections
- Rx - benzylpenicillin (IV) or amoxicillin (PO)