Gram-positive bacteria Flashcards
whats Staphylococcus aureus look like and whats its virulence factors
its a gram positive cocci, forms clusters, does beta haemolysis on blood agar.
catalase positive
coagulase positive
Hospital and community acquired
common infections caused by staphylococcus aureus
skin and wound infections, cellulitis, necrotizing fasciitis, osteomyelitis, septic arthritis, acute endocarditis, pneumonia
treatments for staphylococcus aureus
Flucloxacillin
if its methicillin resistant then its a vancomycin
what does staphylococcus epidermidis look like and whats its virulence
gram positive cocci in clusters. catalase positive, coagulase negative. HAI
what infections can staphylococcus epidermidis cause
biofilm-associated infections: IV lines, CVC, UTI, endocarditis
what do we treat staphylococcus epidermidis with
theres a risk of flucloxacillin resistance in which can use vancomycin.
otherwise use flucloxacillin
what does streptococcus pyogenes look like and whats its virulence factors
gram positive cocci in chains. catalse negative. beta haemolysis on a blood agar. bacitracin sensitive, group A streptococcus
what things does streptococcus pyogenes cause
URTI - pharyngitis. Rheumatic fever, cellulitis, wound infection
what do we treat streptococcus pyogenes with
penicillin, macrolides
what does streptococcus agalactiae look like and its virulence factors
gram positive cocci in chains. catalase negative, beta haemolysis on blood. group B streptococcus
what does streptococcus agalactiae cause
neonatal infections - pneumonia, sepsis and meningitis
what do we treat streptococcus agalactiae with
penicillin +/- gentamicin
what does streptococcus pneumoniae look like and its virulence factors
gram positive cocci in pairs - diplococci
alpha haemolysis on blood agar
catalase negative, optochin sensitive
bile soluble
what does streptococcus pneumoniae cause
pneumonia obviously
meningitis in older people
what are the treatment options for streptococcus pneumoniae
if penicillin-susceptible then use amoxicillin
if resistant use vancomycin, cephalosporins, macrolides, fluoroquinolones