Gram Positive Bacilli Flashcards
Ubiquitous Microorganisms
Gram Positive Rods
Most important and only aerobic member
Spore-former: Bacillus
Non-Fastidious Organisms
Regular Gram Positive Rods
Can be fatal and Deliberating. Humans are infected due to accident encounter
Spore-Former: Bacillus
Types of gram positive rods
Spore-former
Non-spore former
BRANCHING, NON-SPORE-FORMING
6 non-spore forming rods
CARLEG
1. Corynebacterium
2. Arcanobacterium
3. Rhodococcus
4. Listeria
5. Erysipelothrix
6. Gardnerella
Not regularly aerobic. Is a normal flora of GIT, Vagina, and skin
Lactobacillus
Branching, Non-spore former
Nocardia
Found in waste materials
Saprophytic Bacteria
Plant associated organism. Cold-loving
Listeria
Part of the carcasses of animal meat. Occupation-associated infection
Erysipelothrix rushiopathieae
Opportunistic soil microorganism
Bacillus anthracis
Interaction with domesticated animals
Corynebacterium diptheriae
Frequency of isolation is increasing in
Immunocompromised individuals
Transform from vegetative to endospore (protection of genetic make-up)
Spore-former Aerobic rods
Gram positive to gram negative in 48 hours. What process?
Aging or Dessication
Bacillus is commonly found in
Nature
Bacillus is aerobic (T or F)
True
Agent of Anthrax
Bacillus Anthracis
A disease in livestock
Anthrax
3 Pathogens used as agent of Bioterrorism
Bacillus Anthracis
Yersinia pestis
Francisella tularensis
BaYe ni Francis
Causes food poisoning
Bacillus cereus
Causes gastrointestinal illness. Common lab contaminant
Bacillus subtilis
Bacillus anthracis is hemolytic on sheep blood agar (T or F)
False
Virulence factors of Bacillus anthracis
- Polypeptide Capsule
- Potent exotoxin
Capsule of Bacillus anthracis is resistant to Hydrolysis by?
Host proteolytic enzymes
Prevents WBCs from eating the microorganism.
Polypeptide capsule with D glutamic acid
Toxins of B. anthracis
EF - Edema Factor
PA - Protective antigen
LF - Lethal Factor
4 ways to Transfer Genetic Material through genetic combination
- Conjugation
- Transposons
- Transduction
- Transformation
Jumping genes
Transposons
TRANSPO - mo transport siya so mo jump siya. G?
Uses a Vector virus
Transduction
Naked DNA inserts into living DNA
Transformation
mo transform kay naay new DNA
Associated with sheep specifically the WOOL
Woolsorter’s disease/Ragpicker’s Disease
Malignant Pustule
Cutaneous Anthrax
Cutaneous Anthrax enter the body through?
Skin (Cut or Sore)
Most common form of Anthrax
Cutaneous Anthrax
Organism has settled underneath the tissues
Eschar
Formed by anthrax bacteria that occur in soil
Anthrax spores
Target of Bioterrorists
Pulmonary anthrax
Eating undercooked meat from infected animal
Gastrointestinal anthrax