Gram Negative Rods Flashcards

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1
Q

Why are gram negative rods difficult to treat?

A

They produce beta-lactamases.

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2
Q

What is special about non-fermentative gram negative rods

A

Don’t utilise glucose via the fermentative pathway.

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3
Q

What does pseudomonas aeruginosa cuase?

A

Very resistant to antibiotics, is a common cause of nosocomial infections.

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4
Q

What is the oxidase test?

A

Detects presc=ence of cytochrome oxidase, an enzyme in some bacteria.

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5
Q

What do bacteria of genus Stenotrophomonas do?

A

Cause nosocomial infections - similar to P. aeruginosa.

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6
Q

What does Burkholderia pseudomallei do?

A

Causes meliodosis - pneumonia, abscesses and septicaemia

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7
Q

What do bacteria of genus acinetobacter do?

A

Cause nosocomial infections.

Also responsible for community acquired pneumonia associated with smoking and alcoholism

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8
Q

What do the HACEK group of bacteria all cause, and where to they often live in the human body?

A

Endocarditis - are commensals of the human oropharynx.

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9
Q

List five groups of bacteria classified under “Fastidious Gram Negative Rods’

A
HACEK group
Pasteurella
Bordetella
Brucella
Bartonella
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10
Q

What does pasteurella multocida cause, and how it is commonly acquired?

A

Causes infection of skin/soft tissue following bite from cat/dog - commensals of cat/dog mouths

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11
Q

What does Bordetella pertussis cause?

A

Whooping cough.

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12
Q

What do bacteria of genus Brucella cause. and how is it commonly acquired?

A

Cause brucellosis - fever/sweat/joint pain etc.

Zoonotic disease acquired from farm animals and their products (e.g. infected dairy)

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13
Q

What does Bartonella henselae cause and how is it acquired?

A

Cat scratch disease

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14
Q

What does bartonella quintana cause?

A

Trench fever - transmitted by lice.

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15
Q

In what sort of environment might you find bacteria of genus legionnella?

A

Aquatic environments.

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16
Q

What does legionella pneumophila cause?

A

Legionnaire’s disease - pneumonia

17
Q

A patient presents with pneumonia after contact with potting mix and compost. What might he be infected iwth?

A

Legionella longbeachae - found in potting mix. A cause of community acquired pneumonia.

18
Q

What does haemophilus ducreyi cause?

A

Genital lesions - chancroid

19
Q

What feature is special about Haemophilus influenza?

A

Has a polysaccharide capsule that endows virulence, and can be typed.