Gram +ccoci

Question 1

Enterotoxin have resistant from what?

Answer 1

1. faierly heat
2. stomach acid
3. enzymes in stomach and jejunum

Question 2

How many immunonlogic types of enterotoxin?

Answer 2

6 
A
B
C
D
E
F

Question 3

The enterotoxin stimulate…. in GI

Answer 3

Large amount of IL1+IL2 from macrophagesand Th cells

Question 4

The toxic shock syndome toxib result from

Answer 4

Menstrual….or wound infections or nasal packing that used to to stop bleeding

Question 5

مين يلي بتصير عندهم اكثر اشي toxic shock syndrome

Answer 5

الناس يلي ما عندهم antibody ضد TSSTجين

Question 6

Exfoliatinعلى ايش بتاثر وعلى مين اكثر اشي؟

Answer 6

على الskin وبتاثر اكثر اشي young children

بتسببscaleded skin syndrome

Question 7

What is rhe most important leukocidin ?

Answer 7

1.alpha toxin
((Necrosis of the skin and hemolysis)
2.p_v leukocidin
((Pore-forming toxin that kill cells , esp WBC by damaging cell mem))

Question 8

What is the cytotoxic effect of the alpha toxin

Answer 8

1. Formation of holes in cell.mem

2. loss of low molecular weight substance from damaged cell

Question 9

الجين يلي بيعمل encoding للp_v leukocidin باي phage?
شو بيعمل هاد الحج؟
كم نسبة البكتريا من نوع الaurus يلي عندها هاد السم

Answer 9

In lysogenic phage
بيعمل شغلات شنعه زيه
Severe necrotizing pneumonua that caused by 
S.aureus يلي عندها هاد السم 
تقريبا ٢%

Question 10

What is the enzymes that iculde in s.aureus?

Answer 10

1. coagulase
2. fibrinolysin
3. Hyaluronidase
4. protease
5. nuclease
6. lipases
7. staphylokinase

Question 11

شو شغل coagulase

Answer 11

بيعمل clotting plasma وبيحيط بالinfected site وبيمنه وصول الneutrophilلمكان الاصابة

Question 12

شو الانزيمين يلي بيشتغلو عكس بعض

Answer 12

Coagulase and staphylokinase

Question 13

الS.aureus وين بتنتقل وبتسبب مرض؟

Answer 13

Skin , soft tissue , bone , joint , lung , heart and kidney.

Question 14

شو الامراض يلي بتصير في skin and soft tissue
شو سببها
مين اكثر بتسبب hospital ولا community

Answer 14

Impetigo , abcess , cellulitis , folliculitis , conjunctivitis
Post partum breast infection ((mastitis))

سببها الMRSA strains يلي بتنتج p-v leukocidin
Communityاكثر

Question 15

For TSS is characterized by…..

Answer 15

Fever and hypotension and invovlement of three or more of these organ
Liver,kidney , gi, CNS , muscle or blood

Question 16

Scalded-skin syndrome is characterized by

Answer 16

fever, large bullae, and an erythematous rash,
large areas of skin slough, serous fluid exudes,
and electrolyte imbalance can occur. (occurs
most often in young children).

Question 17

S.epudermis ايش بتنتج

وشو اكثر اشي بتسبب

Answer 17

بتنتج الglycocalyx

1. Sepsis in neonates
2. peritonitis in patients with renal failyre حصوصا الناس يلي بتعمل غسيل لل peritoneal

Question 18

شو اهمية الglycocalyx للs.epidermis

Answer 18

بتساعد على الالتصاق مع زراعه اي اشي صناعي مش زي لما ينزرع وما يكون على البكتيريا الglycocalyxمش كثير رح ياثر

Question 19

S.epidermis hospital accqired or community

Answer 19

Hospital

Question 20

S.saprophyticus is H or C

وين مشهورة

Answer 20

Community

بالuti

Question 21

Staphylococcus aureus produces a carotenoid pigment called

.

Answer 21

staphyloxanthin, which gives a golden color to its colonies

Question 22

More than 90% of S. aureus strains contain plasmids that encode
.

Answer 22

a-lactamase, the enzyme that degrades many, but not all, penicillins

Question 23

Teichoic acids are polymers of ribitol phosphate.

Answer 23

They mediate

adherence of the staphylococci to mucosal cells.

Question 24

Lipoteichoic acids

play a role in the induction

Answer 24

of septic shock by inducing cytokines such
as interleukin-1 (IL-1) and tumor necrosis factor (TNF) from
macrophages.

Question 25

Exfoliatinاحكيلي عن

Answer 25

بيسبب scalded skin syndrome

وبيتصرف ك protease that cleave the desoglein in desmosome to separation of the epidermis at the granular cell layer.

Question 26

S.aureus تعمل غلى انتاج الgolden yelllow

شو نوع الhemolytic

Answer 26

Beta hemolytic

Question 27

Such organisms can be treated with

β-lactamase–resistant penicillins (

Answer 27

e. g., nafcillin or
cloxacillin) , some cephalosporins, or
vancomycin) .

Question 28

Other treatment to s.aureus

Answer 28

⚫ Treatment with a combination of a
β-lactamase–sensitive penicillin (e.g., amoxicillin)
and a β-lactamase inhibitor (e.g., clavulanic acid)
is also usefu

Question 29

شو احسن علاج للMRSA infection

Answer 29

Ceftaroline fosamil

Question 30

Pooled serum globulins ايش بيعمل

Answer 30

بيحتوي على اجسام مضادة antibodies against TSST

التي تستخد لعلاج الtoxic shock syndrome