Grab Bag Flashcards
Methymethacrylate
Bone cement implantation syndrome:
* hypoxia, hypotension
* supportive tx
* anesthesia cannot prevent
* surgeon can lower wash pressure + drill holes
Equation for PaO2 changes with age
PaO2 = 100 - (age/3)
Suspect and TX Bronchospasm
Suspect @ elevated Paw + near induction/extubation + hypoxia
auscultate chest - can be wheeze
Tx:
* 100% FiO2
* albuterol puffs
* deepen with volatile > propofol
* small bolus epinephrine
* ketamine
* magnesium
* terbultaine
causes of post-op polyruia
central DI
nephrogenic DI
SIADH
osmotic - mannitol, glucose
overhydration
Poor R wave progression
LVH
RVH
anterior MI
wnl
Causes of PVC
increase catecholamines @ sugery/anxiety
∆ lytes : hypoK, hypoMg, hyperC
Normal CBF
Ischemic CBF
death CBF
50-55 cc/min/100g
18-20 cc/min/100g
8-10 cc/min/100g
A s/e terbutaline
hypotension
palpitations
CP
pulmonary edema
hypokalemia
hyperglycemia
Treat hemophilia A intraop coagulopathy
(-) VIII
can give VIII but quickly develop abx and become refractory»_space; treat with PCC (has proteases that will breakdown abx, short life) and VIIa (stabilizes downstream coag pathways)
Oligura ddx PRE/INTRA/POST
factor→pre/intra/post:
Usmo→ >500/ <350/∆
UNa→ <10/>10/∆
FeNA → <1/>2%
FeNa formula
FeNa = (Una x Pcr) / (UCr x Pna)
lyte ∆ at CRF
HYPERK, HYPERPO4, HYPERMg
HYPER uric acid, HYPERlipid, HYPERsulphate
hypoNa, hypoCa, hypoalbimin
AG metabolic acidosis
Neuraxial and LMWH/enoxaparin/lovenox ppx qd
HOLD BEFORE NEEDLE: 12 hours
RESTART AFTER NEEDLE: 12 hours
HOLD BEFORE CATH OUT: 12 hours
RESTART AFTER CATH OUT: 4 hours
Neuraxial and LMWH/enoxaparin/lovenox ppx BID
HOLD BEFORE NEEDLE: 12 hours
RESTART AFTER NEEDLE: 12 hours
HOLD BEFORE CATH OUT: remove before starting, do not use this does while catheter in. SPINAL HEMATOMA
RESTART AFTER CATH OUT: 4 hours
Neuraxial and LMWH/enoxaparin/lovenox therapeutic
dose is 1 mg/kg q12 OR 1.5 mg/kg daily
HOLD BEFORE NEEDLE: 24 hours
RESTART AFTER NEEDLE: 24 after non high bleeding risk surgery OR 72 hours after high bleeding risk surgery
HOLD BEFORE CATH OUT: remove before starting, do not dose this way when catheter in SPINAL HEMATOMA
RESTART AFTER CATH OUT: 4 hours
Neuraxial and SQ heparin ppx BID or TID
HOLD BEFORE NEEDLE: 4-6 hours OR check coags
RESTART AFTER NEEDLE: immediately
HOLD BEFORE CATH OUT: 4-6 hours
RESTART AFTER CATH OUT: immediately
Neuraxial and SQ heparin ppx high dose BID or TID
HOLD BEFORE NEEDLE: 12 hours and coags
RESTART AFTER NEEDLE: unknown
HOLD BEFORE CATH OUT: unknown
RESTART AFTER CATH OUT: immediately
Neuraxial and SQ heparin therapeutic
HOLD BEFORE NEEDLE: 24 hours and coags
RESTART AFTER NEEDLE: not recc with catheter in place
HOLD BEFORE CATH OUT: not recc with catheter in palce
RESTART AFTER CATH OUT: immediately
Neuraxial and bypass heparin
HOLD BEFORE NEEDLE: avoid
RESTART AFTER NEEDLE: 60 minutes
HOLD BEFORE CATH OUT: after normal coagulation restored
RESTART AFTER CATH OUT: n/a
Neuraxial and IV heparin
HOLD BEFORE NEEDLE: 4-6 hours and normal coags
RESTART AFTER NEEDLE: 1 hour
HOLD BEFORE CATH OUT: 4-6 hours and normal coags
RESTART AFTER CATH OUT: 1 hour
Neuraxial level @ C/S
T6 hyperbaric
Neuraxial level @ cervical cerclage
T10 hyperbaric
Neuraxial level @ hips
> T12 isobaric
Neuraxial level @ knees
> T12 isobaric
Neuraxial level @ TURP
> T10 of iso or hyperbaric
Treat unstable narrow regular tachycardia
SYNC CARDIOVERT 50-100 J
Treat unstable narrow irregular tachycardia
SYNC CARDIOVERT 120-200 J
Treat unstable wide regular tachycardia
SYNCO 100 J
Treat unstable wide irregular tachycardia
DEFIB 360 J (polymorphic VT)
Mg at torsades
Test dose composition
1.5% lidocaine with 1:200 000 epinephrine
Ekg leads to use intraop
V5 - 75%
V5 + V4 - 90%
V5 + V4 + II - 96%
change of detecting ischaemia
ddx Myasthenic crisis from cholinergic crisis
use edrophonium or tensilon test
MG > weakness will worsen
CC > weakness will improve
Treat cholinergic crisis
supportive w/ possible intubation
d/c anticholinesterase therapy
begin anticholinergics
IVIG
Treat myasthenic crisis
supportive
IVIG
plasmaphoresis
RF in MG for postop mechnical ventilation
- duration of disease > 6 years
- pyridostigmine > 750 mg/day (usually q6h regiment)
- concomitant pulmonary disease
- PIP < -25 cmH2O
- VC < 40 /kg
Extubation criteria: simplified
- hemodynamically stable
- adequately reversed
- awake and alert
- spontaneously ventilating
- VT 6-9 cc/kg
- RR 12-20 with ETCO2 35-40 mmHg
Extubation criteria: detailed
- VC > 15 cc/kg
- pH > 7.3
- PaO2 > 60 mmHg on FiO2 > 50%
- Max NIF > -20
- RR < 30
Treat venous air embolism
Saline onto surgical field
Bone was onto exposed surfaces
aspirate from CVL
gentle compression of IVC
supportive
HSV and neuraxial in pregnancy?
Primary and not treated > contraindicated, possible viremia
Secondary and treated > indicated, low risk viremia
MH vrs thyroid storm
MH: hyperK, rigid, increased CK, lactic acidosis, intraop
Thyroid storm: hypoK, not rigid, no CK, no lactate, postop
Treat MH
dantrolene 2.5 mg/kg
nondepol will not cause paralysis
Treat Thyroid storm
PTU
beta blockers
iodinated contrast
steroids
acetaminophen
reserpine to deplete
Treat neuroleptic syndrome
bromocriptine
+/- dantrolene
stop haldol
nondepol MB will result in flaccid paralysis
Treat serotonin syndrome
cyproheptadine
stop serotonergic meds
drugs dosed by IBW
nondepol NB
drugs dosed by TBW
sux
opioids
propofol gtt
drugs dosed by LBW
propofol induction
TX TURP syndrome
stop irrigation
fluid restriction if Na >120 and symptomatic
hypertonic saline if Na <120
intubated
loop diuretics
benzos for seizures
Nitroprusside toxicity metabolits
cyanomethemoglobin
thiocyanate
cyanide toxicity > MvO2 increases
Tx Nitroprusside toxicity
stop nitroprusside
sodium thiosulfate
inhaled amyl nitrates
hydroxycobalamine
consequences of hyperglycemia
- decreased immune function
- increased oxidative stress
- endothelial dyd
- increased inflammatory factors
- increased procoagulant state
- fluid shifts
- electrolyte ∆
@ surgery - decreased wound healing
- increased infections
- delayed recovery
- end organ failure @ heart, brain, kidney
Sx of hypoglycemia under GA
cant see confusion
maybe diaphoresis
Suspect if concern for light anesthesia = SNS activation