GR Flashcards
Acid base rcn given by grignard reagent
OH, NH2, SH
ACETIC ANHYDRIDE
CH3—NO2 ( METHANE PR LAGE PROTON KI ACIDIC STRENGTH PHEONLIC PROTON KE BBARABAR HOTI HAI
Such type of rxn k/as ziritnoff rxn
Transmetallation rxn given by grignard reagent
R’MgX + RCuli = R’Culi +RMgX
Exchange of ch3-
Ester +GR=
Amide+GR=
Alcohol
Ketone
RMgX give 1,2 or 1,4 addition in alpha beta unsaturated carbonyl compound
1,2
Carboxylic acid +RMgX
RH
Imagine the structure of Et2SO4
≈ Et –OTs
Electrophile is Et
GR follow which mechanism SN1 OR SN2
SN2
Large group syn to carbonylgroup attack from
Medium side
Large group anti to carbonyl attack from
Small side group
GR act as a base or nucleophile
So at same time it act as both
Kukinkouich rxn me kya Hota hai
Ester + grignard(at least 2 carbon)/ alkene = cyclopropane
Kylin rxn ko pahchane kaise
GR reagent ke sath Titanium diya hoga
Kylin rxn me jab substrate me dono reagents given ho to
Ester alkene se he react karega
Intermediate formed during kylin kobich rxn
3 ,5 membered ring formed