GP Flashcards
1
Q
Initial investigations in coeliac disease?
A
TTG antibodies
Endomyseal antibodies
2
Q
Gold standard for coeliac diagnosis?
A
Endoscopic intestinal biopsy - duodenum
3
Q
Findings of biopsy in coeliac disease?
A
Villous atrophy
Crypt hyperplasia
Increased intraepithelial lymphocytes
4
Q
Which gene associated with coeliac disease?
A
HLA-DQ2 and HLA-DQ8
5
Q
Investigations for colitis?
A
Colonoscopy and biopsy (flexi sig)
6
Q
Findings on colitis biopsy?
A
Ulceration
No inflammation beyond submucosa
Continuous
Crypt abscesses
Pseudopolyps
7
Q
Findings on crohn’s biopsy?
A
Inflammation in all layers
Skip lesions
Increased goblet cells
