GP Flashcards

1
Q

6 causes of cauda equina?

A

Malignancy:
Bony mets
Myeloma
Primary sacral tumour e.g. chordoma

Infection:
Epidural abscess

Trauma:
Disc prolapse
Epidural haematoma

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2
Q

What to do if a patient presents to GP with cauda equina?

A

Arrange urgent same day spinal surgery admission

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3
Q

How to tell the difference between cauda equina and cord compression?

A

Cauda equina compression causes flaccid paralysis with loss of reflexes
Cord compression usually causes spastic paralysis with brisk reflexes
Both cause sensory and power loss.

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4
Q

Red flag symptoms of lower back pain?

A
Bilateral sciatica
Bladder dysfunction
Perianal paraesthesia
Gait disturbance
Lower limb weakness
Erectile dysfunction
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5
Q

SEs of metformin

A

GI upset - nausea & diarrhoea
Lactic acidosis (if renal failure)
Caution in RF if eGFR <30

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6
Q

What score can be used to calculate risk of CVD or stroke in the next 10 years? What age is it valid until?

A

QRisk2

84 years

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7
Q

Give some examples of meds used in migraine prophylaxis?

A

Amitryptiline
Propranolol
Topiramate

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8
Q

Mx of acute migraine?

A

Triptans

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9
Q

How to confirm Dx of HTN?

A

clinic blood pressure of 140/90 mmHg or higher AND

ABPM daytime average or HBPM average of 135/85 mmHg or higher

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10
Q

Beta-blocker CIs?

A
asthma
cardiogenic shock
marked bradycardia
hypotension
third degree AV block
severe peripheral arterial disease
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11
Q

prophylaxis of chronic tension headache?

A

Amitriptyline

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12
Q

When to give abx in tonsillitis?

A

FeverPAIN score 2-3: consider delayed antibiotic prescription
FeverPAIN score 4-5: consider immediate antibiotic prescription

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13
Q

FeverPAIN criteria?

A
Fever
Pus
Symptom onset <3 days
Inflamed tonsils
No cough/coryza
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14
Q

Tonsillitis tx?

A

Penicillin V (500mg QDS for 10 days) is the treatment of choice with erythromycin or clarithromycin being the choices for those allergic to penicillin

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15
Q

Dukes staging colorectal cancer?

A

Dukes A – tumour confined to bowel wall
Dukes B – tumour has gone through wall but not into nodes
Dukes C – tumour involving regional nodes
Dukes D – distant metastases are present

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16
Q

How to prescribe buproprion in patients trying to quit smoking?

A

Bupropion 150 mg OD for 6 days, increasing to 150 mg BD for a total of 7–9 weeks
Ask them to stop smoking 7-14 days after starting buproprion

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17
Q

Who should get a lower dose of buproprion?

A

elderly
patients who have mild to moderate liver impairment
renal impairment where GFR <50 mL/min.

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18
Q

CIs to buproprion?

A

Seizures
CNS tumour
Severe hepatic cirrhosis
Hx of BPD, anorexia or bulimia

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19
Q

Risk of PE after AZ vaccine? What to do if they come in?

A

4-28 days

Send to A&E for platelet count (if low high chance)

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20
Q

3 types of melanocytic naevi?

A

Compound naevi have nests of cells at the epidermal-dermal junction as well as within the dermis. They tend to have a raised area surrounded by a flat pigmented area.
Junctional naevi have nests of cells at the epidermal-dermal junction. They tend to be flat and coloured.
Dermal naevi have nests of cells in the dermis. They tend to raised and can be skin coloured or pigmented.

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21
Q

Benefits of metformin?

A

Moderately effective glycaemic control (GC)
Weight loss
CV protection

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22
Q

Benefits of sulfonylureas (gliclazide)?

A

Highly effective glycaemic control

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23
Q

SEs of sulfonylureas (gliclazide)?

A

Risk hypos
Weight gain
Caution renal impairment

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24
Q

Benefits of Gliptins (Sitagliptin/Linagliptin)?

A

Weight neutral

Good in CKD

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25
SEs of Gliptins (Sitagliptin/Linagliptin)?
Least effective GC | potential risk HF
26
Benefits of Pioglitazone?
Mod effective GC | safe in renal impairment
27
SEs of Pioglitazone? ELBOW
``` Edema (can worsen HF) Liver impairment Bladder cancer Osteoporosis (fractures) Weight gain ```
28
Benefits of SGLT2 inhibitors? (Empagliflozin)
Mod effective GC weight loss CV benefits
29
SEs of SGLT2 inhibitors (Empagliflozin)?
Genital infections DKA Amputation Caution eGFR <60
30
Benefits of GLP-1s (injectable) (Exenatide)?
Highly effective GC Weight loss CV benefits
31
SEs of GLP-1s (injectable) (Exenatide)?
Cancer (breast) | Expensive
32
Benefits of insulin?
Highly effective GC
33
SEs of insulin?
Weight gain
34
Another name for seborrheic keratoses?
Basal cell papilloma
35
Standard uncomplicated UTI Tx in women?
Trimethoprim 200mg BD for 3 days | Nitrofurantoin 100mg modified release BD for 3 days (eGFR >40)
36
Pyelonephritis tx?
Cephalosporin or co-amoxiclav for 7-10 days | Review in 24-48 hours if not in hospital
37
When to organise USS in kids with UTI?
1. In acute infection in all children with atypical features – poor urinary flow, abdominal/bladder mass, raised creatinine, sepsis, treatment failure, non-E.coli organism. 2. During acute illness in children <6 months with recurrent UTIs 3. Within six weeks, for children aged >6 months with recurrent UTIs 4. Within six weeks, for all children <6 months of age with first time UTI that responds to treatment.
38
What dose is used in UTI prophylaxis?
Reduced dose - usually 25-50% normal dose
39
Which additional blood tests should be done if a patient's LDL comes back increased?
TFTs LFTs U&Es Fasting glucose
40
How does Bezafibrate act?
reducing serum triglycerides
41
Common SEs of statins?
Asthenia Headache Flatulence
42
Causes of secondary hypercholesterolaemia?
``` Obesity CKD Alcohol excess Anorexia Uncontrolled hypothyroidism Thiazide diuretics and ciclosporin ```
43
Which drugs are cautioned when a patient is taking a statin?
Clarithromycin | Grapefruit juice
44
How to manage faecal impaction?
Combination of movicol orally and phosphate enemas
45
Which laxative is used for bowel prep?
Picolax (sodium picosuphate with magnesium citrate)
46
How to convert morphine from oral to SC?
Half the dose
47
What anti-emetic is used in opioid induce nausea?
Metoclopramide 10mg TDS
48
What type of nausea is cyclizine useful against?
Bowel obstruction Raised ICP Motion sickness
49
When to stop statins due to myopathy?
If CK is 5-10x higher than normal
50
When to stop statins due to abnormal liver function?
If LFTs are 3x higher than normal
51
When to stop and restart pill due to surgery?
Stop 4 weeks before | Restart 2 weeks after
52
What CHADsVASc score is needed for tx in AF?
2+
53
Which type of ulcer is better after eating?
Duodenal
54
Why do we check U&Es after starting an ACEi?
Renal artery stenosis
55
What is does a feeling of heartbeat stopping followed by pounding suggest?
Ectopic supraventricular beats
56
Superficial thrombophlebitis tx?
NSAID
57
Hypertensive retinopathy stage 1 fundoscopy?
Arteriolar narrowing and tortuosity | Increased light reflex - silver wiring
58
Hypertensive retinopathy stage 2 fundoscopy?
Arteriovenous nipping
59
Hypertensive retinopathy stage 3 fundoscopy?
Cotton-wool exudates | Flame and blot haemorrhages
60
Hypertensive retinopathy stage 4 fundoscopy?
Papilloedema
61
standard antibiotic prophylaxis in patients with COPD?
Azithromycin
62
Target BP in clinic?
* If <80y/o - 140/90 * If >80y/o - 150/90 * If T2DM - 140/90 (130/80 if end organ damage) * If T1DM - 135/85 (130/80 if end organ damage)
63
When to refer cardiac chest pain from GP?
current chest pain or chest pain in the last 12 hours with an abnormal ECG: emergency admission chest pain 12-72 hours ago: refer to hospital the same-day for assessment chest pain > 72 hours ago: perform full assessment with ECG and troponin measurement before deciding upon further action
64
What to do if someone on immediate release metformin is struggling with SEs?
Switch to modified release and uptitrate whilst monitoring symptoms
65
Sick day rules for DM?
Increase frequency of blood glucose monitoring to four hourly or more frequently Encourage fluid intake aiming for at least 3L in 24hrs If unable to take struggling to eat may need sugary drinks to maintain carbohydrate intake Do not stop insulin
66
Otitis externa tx?
Topical antibiotic or combined topical antibiotic + steroid Just antibiotics: Gentamicin/Chloramphenicol drops Antibiotics + corticosteroids • Dexamethasone + ciprofloxacin OR • Betamethasone + Neomycin sulphate
67
What to do if someone's urine albumin:creatinine ratio >3mg/mmol and they have known diabetes?
Start ACEi
68
When to refer to nephrology based off ACR?
ACR >70 and not known to have DM ACR >30 + persistent haematuria (ruled out UTI) ACR 3-29 + persistent haematuria + declining eGFR/CVD
69
Glaucoma screening if positive family history?
Annual screening from 40 years old
70
What is diabetic retinopathy stage 1 and what are the features?
Mild non-proliferative diabetic retinopathy | 1 or more microaneurysm
71
What is diabetic retinopathy stage 2 and what are the features?
``` Moderate NPDR microaneurysms blot haemorrhages hard exudates cotton wool spots ```
72
What is diabetic retinopathy stage 3 and what are the features?
Severe NPDR blot haemorrhages and microaneurysms in 4 quadrants venous beading in at least 2 quadrants intraretinal microvascular abnormalities in at least 1 quadrant
73
What is diabetic retinopathy stage 4 and what are the features?
Proliferative diabetic retinopathy retinal neovascularisation - may lead to vitrous haemorrhage fibrous tissue forming anterior to retinal disc
74
What is the last stage of diabetic retinopathy and what are the features?
Diabetic maculopathy based on location rather than severity, anything is potentially serious hard exudates and other 'background' changes on macula
75
How is bowel cancer screened for and who is it offered to?
FIT test | Men and women aged 60 -74