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Rheumatoid arthritis, osteoarthritis, gout > Gout > Flashcards

Gout Flashcards

1
Q

MOA allopurinol

A

Competitive inhibitor of xanthine oxidase- blocks conversion of hypoxanthine to uric acid

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2
Q

MOA febuxostat

A

Non competitive xanthine oxidase inhibitor

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3
Q

MOA probenecid

A

Organic acid transport inhibitor that decreases renal uptake of uric acid

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4
Q

MOA lesinurad

A

Highly potent inhibitor of renal uric acid reuptake - targets urate transporter URAT1. CI if eGFR <45

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5
Q

Risk factor causing gout by increased crystal formation

A

OA

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Rheumatoid arthritis, osteoarthritis, gout (6 decks)

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