Gout Flashcards
1
Q
Diagnosis of gout
A
Monosodium urate crystals in joint fluid
Crystals are needle shaped and negatively birefringent crystals
2
Q
Features of acute gout
A
Monoarticular arthritis of first MTP or tarsal joint
If it presents at first MTP(podagra), joint aspirate not required
3
Q
Transplantation gout
A
Associated with use of cyclosporine(calcineuron antagonist)
4
Q
Lifestyle modifications to treat gout
A
Purine restriction, weight loss, discontinue etoh,
D/c thiazides diuretics, low dose salicylates
5
Q
Acute flair treatment
A
-1st line: NSAIDs, use steroids if NSAIDs not safe
Joint injection meds ineffective
6
Q
2 or more attacks per year or presence of tophi or kidney stones
A
Start allopurinol(>300mg/day), goal serum Uric acid
7
Q
3 stages of gout
A
- a symptomatic hyperuricemia: lasts several decades
- acute intermittent gout
- chronic tophaceous gout
