Goulds Chpts 1,2,6,7,8 Flashcards

1
Q

Pathophysiology

A

Study of functional (physiologic) changes in the body as a result from a disease process

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2
Q

Pathogenesis

A

Refers to the development of the disease or the sequence of events involved in the tissue changes related to the specific disease process

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3
Q

Homeostasis

A

Maintains a relative stable environment regardless of external changes

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4
Q

Microscopic

A

Cellular level. Can only see with a microscopy

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5
Q

Diagnosis

A

Identification of a specific disease through evaluation of signs (objective:example fever) symptoms (subjective: example “sharp pain”)

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6
Q

Etiology

A

Causative factors in a particular disease

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7
Q

Idiopathic

A

The cause of the disease is unknown

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8
Q

Iatrogenic

A

When a treatment, procedure or physician error cause a disease

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9
Q

Predisposing factors

A

“High-risk” factors that have the tendencies to promote the development of a disease in an individual.
Example: age, race, gender, habits

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10
Q

Prophylaxis

A

Preventive measure to spread disease

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11
Q

Insidious onset

A

The start of the disease is a gradual progression with only vague or mild signs

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12
Q

Acute disease

A

A short-term illness that develops quickly.

Sudden, severe

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13
Q

Chronic disease

A

A milder condition that develops gradually but persists for a long period of time

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14
Q

Subclinical

A

Pathologic changes occur but no obvious manifestations are exhibited by the patient.

Example kidney damage progressed to advance stages of renal failure before symptoms manifested.

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15
Q

Latent stage

A

After exposure to a disease it is the Silent stage with no clinical evidence, signs or symptoms but the probably communicable (easily spread to others)

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16
Q

Parethesias

A

“Pins & needles” sensation

Common in hypo- and hyper- kalemia

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17
Q

Cardiac dysrhythmia, neuromuscular deficiency, paresthesias, shallow breathing and renal failure are all signs of what type of blood disorder?

A

Hyperkalemia

And hypokalemia

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18
Q

What impact does hypokalemia have on the body?

A

Cardiac dysrhythmia, neuromuscular deficiency, paresthesias, shallow breathing, renal failure

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19
Q

Disease

A

Deviation from the normal state of health or homeostasis

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20
Q

Acidosis primarily effects what system in the body?

A

Nervous system

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21
Q

This substance is used to fight microorganisms on living tissue

A

Antiseptic

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22
Q

Condition with the prescence of nits at the base of hair shaft

A

Pediculosis (Lice)

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23
Q

Predicted outcome or likelihood of recovery from a specific disease

A

Prognosis

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24
Q

Name for white blood cell

A

Leukocyte

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25
Q

Maintenance of a stable internal environment regardless of the outside environment

A

Homeostasis

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26
Q

A very severe, systematic allergic reaction and may be fatal

A

Anaphylaxis

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27
Q

This condition usually indicates the presence of a bacterial infection

A

Leukocytosis

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28
Q

Microbes present in the blood, specifically bacteria

A

Septicemia

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29
Q

Higher number of cases of infectious disease in many regions across the globe

A

Pandemic

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30
Q

Cellular adaptation in which the cell size decreases

A

Atrophy

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31
Q

This substance used to fight microorganisms on non living surfaces

A

Disinfectant

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32
Q

Hansen’s disease that is caused by bacterium

A

Leprosy

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33
Q

A collection of signs and symptoms that usually occur together in response to a certain condition

A

Syndrome

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34
Q

Layer of skin that lacks blood vessels and nerves.

A

Epidermis

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35
Q

This infection is highly contagious with small vesicles that rupture to produce a crusty brown pruritic mass

A

Impetigo

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36
Q

Hypocalcemia may cause this condition; another name for constant muscle contraction

A

Tetany

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37
Q

This disease deposits collagen in the small blood vessels in the skin and sometimes the viscera

A

Scleroderma

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38
Q

Constant sweating

A

Diaphoresis

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39
Q

Common cause for diaphoresis

A

Hyponatremia

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40
Q

Precipitating factor

A

A circumstance that causes a sudden acute episode of a chronic disease to occur

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41
Q

A disease causing microbe is what?

A

Pathogen

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42
Q

Anaerobic bacterium

A

Thrives in the absence of oxygen

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43
Q

Bacilli bacteria

A

Rod-shaped organisms which include vibrio (curved rods) and pleomorphic (variable and indistinct shape)

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44
Q

Cocci bacteria

A

Spherical shape or berry shape

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45
Q

Strep(to)-

A

Chains

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46
Q

Staph(ylo)-

A

Grape like clusters

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47
Q

Palisade-

A

Refers to bacterial cells lying together with the long sides parallel

48
Q

Pili or fimbriae

A

Tiny hair like structures found on some bacteria

49
Q

Exotoxins

A

Usually produced by GRAM-POSITIVE bacteria and diffuse through body fluids

50
Q

Enterotoxins

A

Toxin Stimulate the vomiting center and cause gastrointestinal stress

51
Q

Endotoxin

A

Present in the cell wall and released after bacterium dies

52
Q

Virus

A

A parasite that requires a living host cell for replication. They mutate easily which makes them hard to control

. I.e. Influenza

53
Q

Name three microorganisms that have similarities to both bacteria and viruses. They replicate by binary fission but require living cells to reproduce.

A

Chlamydiae, rickettsiae, mycoplasmas

54
Q

Fungi is often found where?

A

On dead organic material such as plants promoted by warmth and moisture

55
Q

Tinea pedis

A

Fungal infection on the skin called Athlete’s foot

56
Q

Candida

A

Fungus in the oral cavity is called thrush

57
Q

Protozoa

A

More complex organisms that can live on dead or live organic matter. I.e.: malaria

58
Q

Eukaryotic cells

A

Cells with a nucleus they lack cell walls (except plants) their DNA is enclosed in the nuclear membrane

The opposite is prokaryotic cell, a simple structure with a cell wall

59
Q

Helminths

A

Parasite worms

60
Q

Prions

A

Abnormal molecule transmissible in tissue contaminated with a protein

61
Q

When a group of cells in a body dies, the change is called

A

Necrosis

62
Q

A raised, thin-walled lesion containing clear fluid is called

A

Vesicle

63
Q

Metabolic acidosis is likely to be caused by what prolonged sign

A

Diarrhea

64
Q

A deviation from the normal state of health and function

A

Disease

65
Q

Apoptosis is what?

A

Preprogrammed cell self-destruction

66
Q

Universal precaution

A

Treat everyone like they are sick. Precaution taken assuming all body fluids are possible sources of infection

67
Q

Nosocomial

A

Infections that occur from exposure in a healthcare facility, doctors office, hospital, nursing home

68
Q

A change in a tissue marked by cells that vary in size and shape. Large nuclei are frequently present

A

Dysplasia

69
Q

Deficiency of potassium

A

Hypokalemia

70
Q

The term to Control bleeding

A

Hemostasis

71
Q

A symptomatic person whose body harbors pathogens and can transmit them to others

A

Carrier

72
Q

Increased cell size

A

Hypertrophy

73
Q

Communicable

A

Infectious diseases that can spread from one person to another

74
Q

The science of tracking the pattern or occurrence of a disease

A

Epidemiology

75
Q

Hyperplasia

A

Increased number (quantity) of cells resulting in an enlarged tissue mass

76
Q

Mortality

A

Indicate the relative number of deaths resulting from a particular disease

77
Q

One mature cell type is replaced by different mature cell type

A

Metaplasia

78
Q

Sequelae

A

Unwanted outcome from a primary condition. Example paralysis following a stroke

79
Q

Disease rate within a certain group is called what?

A

Morbidity rate

80
Q

Subjective feelings such as pain or nausea are know as what in the diagnosis?

A

Symptom

81
Q

Ischemia

A

Decreased supply of oxygenated blood to Cells

82
Q

Hypoxia

A

Decreased or insufficient level of oxygen in the tissues

83
Q

Anaplasia

A

Cells that are undifferentiated with variable nuclear and cell structures. Characteristics of cancer

84
Q

Hematocrit and what could elevate it?

A

% of RBC to total blood or whole blood

Dehydration

85
Q

Incubation period

A

The disease process is developing

86
Q

Prodromal

A

Early development of the disease. Signs absent or nonspecific

87
Q

Third spacing fluid

A

Fluid shifts out of blood into body cavity or tissue and can no longer renter vascular compartment

Example ascitis

88
Q

Hypernatremia

A

Too much sodium in the blood

89
Q

Hypokalemia

A

Low potassium in the blood
Effects: cardiac dysrhythmia, neuromuscular functions, paresthesias (pins&needles feeling), shallow respiration, polyuria

Normal range is 3.5-5.0u

90
Q

Low pH less than 7.4

A

Acidosis to much hydrogen ions

91
Q

High pH more than 7.4

A

Alkalosis hydrogen ions are too low

92
Q

Hypocalcemia

A

Low calcium in the blood. Some causes: increased pH level alkalosis, renal failure, hypoparathyroidism

93
Q

Tetany

A

Constant muscle contractions

94
Q

Paresthesias

A

Pins and needles sensation

95
Q

Nevus or Nevi

A

Mole

96
Q

Hemostasis

A

Stop bleeding

97
Q

Bacterial endospore

A

Latent stage. Can’t reproduce. Can survive long periods in adverse conditions

98
Q

Keratin

A

Protein in epidermis that prevents fluid loss from body and letting excessive water into body (while swimming)

99
Q

Epidermis stratum basale

A

Only layer where mitosis occurs

100
Q

Stratum corneum

A

Outer most layer of epidermis made up of mostly dead cells

101
Q

Name 4 types of hypersensitivity

A

1) allergic
2) cytotoxic - IgG react example incompatible blood transfusion
3) immune complex
4) cell mediated or delayed example TB test

102
Q

Pruritic

A

Itchy

103
Q

Purulent

A

Pus

104
Q

Utricaria

A

Hives or Wheals

Hypersensitive type 1

105
Q

Atopic dermatitis

A

Eczema

Dry, scaly, itchy rash

106
Q

Red lesions that develop into a silvery patch

A

Psoriasis

107
Q

Autoimmune disorder causes blisters ( bullae) skin sheds leaving painful open sore

A

Pemphigus

108
Q

Collagen deposits into arterioles or capillaries reducing blood flow

A

Scleroderma

109
Q

Furuncles

A

Boils
Begins are hair follicles
Usually large amount of purulent exudate (pus)

110
Q

Fomites

A

Inanimate objects like doorknobs transmitted bacteria

111
Q

Erysipelas

A

Cellulitis infection of dermis and subcutaneous tissue. Red streaks may develop

112
Q

Acute necrotizing fasciitis

A

Flesh eating disease

Mixture of anaerobic and aerobic bacteria

113
Q

Type of latent disease triggered active by common cold, stress or sun exposure

A

Herpes simplex

114
Q

Verrucae

A

Warts

115
Q

IgG

A

Immunoglobulin
Most common in the blood
Fights infection neutralizes viruses and toxins
Gets transferred from mother to baby

116
Q

IgA

A

Immunoglobulin

Found in mucous secretions

117
Q

IgM

A

Immunoglobulin
Physically the largest antibody produced by B cells. Mostly produced in the spleen it’s the first responder to antigens(foreign bodies)