GOSH Flashcards
What is the most common cause of reduced variability on CTG (short term)
Sleeping fetus
We worry if decreased variability for longer than 40 mins
When should u be careful about ABX on contraception
If you ar taking an enzyme inducing Abx e.g rifampicin during the pill free period then you need to use condos for 7 days
When can you take the COCP post-partum
UKMEC4 if BF<6weeks
UKMEC2 if BF 6wks-6months PP
Also shouldn’t be used in first 21 days PP at all
If started after day 21 additional contraception is needed for first 7 days
What week can pregnant women not fly from
32 weeks
When do you do a fetal blood sampling after CTG interpretation vs emergency C-section
I think mostly go for c-section
Fetal blood sampling can be useful in a non-reassuring CTG (vs abrnomal CTG) but often delivery is prioritized
What in a history would stop you giving labetalol in a pregnant lady for hypertension in pre-eclampsia
What do y give instead
Asthma!
Give nifedipine instead (ccb)
When do you get a tender cervix
PID most commonly
Also in ectopic, endometriosis, appendicitis, ovarian torsion
I guess anything that inflames the peritoneal area
No tender cervix in a miscarriage
Exaggerated symptoms of pregnancy e.g. excessive vomiting plus bleeding plus large fetus
Hydatiform mole
When is surgical Mx indicated over medical in ectopic
Symptoms (pain)
Over 35mm
Visible fetal heartbeat
HCG over 5000
Step wise approach to managing PPH
ABCDE
Warmed Crystalloid infusion (fluids)
Mechanical= rubbing up the fundus, catheter
Medical= IV oxytocin
Surgical= IU balloon tamponade
What is Sheehan’s syndrome
Necrosis of the pituitary gland following hypovolaemic shock as part of PPH
What do you give in magnesium sulphate induced respiratory depression
Calcium gluconate
What is HELLP syndrome
Haemolysis
Elevated Liver enzymes
Low Platelets
What blood test results in Edwards
Everything low
Same tests as downs which is high hCG and high inhibin
Stepwise investigations for reduced fetal movements
Handheld Doppler
If no HB then USS
If HB then CTG for at least 20 mins
First line in infertility in PCOS after weight loss advice
Clomifene
Anti-oestrogen
Drugs In an MTOP
mifepristone followed by prostaglandins after 36-48hrs e.g. misoprostol
What makes you do LSCS over external cephalic version
Breech but waters ruptured
Cutoffs for Hb levels
- First trimester= 110
- Second or third trimester= 105
- PP= 100
When does pregnancy increase blood pressure
After 20 weeks
Skin tears after birth Tx
Category 1= involving skin only- no repair needed
Category 2= skin and perineal muscle- repair on maternity ward
Category 3= skin, perineal muscle and anal sphincter complex- repair in theatre
Category 4= skin, perineal muscle, anal sphincter, rectal mucosa- repair in theatre
How do you treat thrush in pregnancy
Clotrimazole pessary, not oral fluconazole as it is associated with congenital abnormalities
How do you investigate duchenne muscular dystrophy got confirm the diagnosis
Genetic analysis
Creatinine kinase is also a strong indicator
What do you give in urge incontinence when oxybutinin is contraindicated
Mirabegron
CI as fall risk I’m elderly
When do you induce labor in cholestasis of pregnancy and why
37
Increased risk of stillbirth
How do you deliver the next baby with a classical c-section scar
C-section
Vaginal birth is contraindicated
What are the 2 indications for big dose of folic acid (5mg)
anti-epileptic medication
Obese (>30 BMI)
Medical Mx of MTOP
Oral mifepristone
AND
Vaginal prostaglandins (e.g. Misoprostol)
What do you do if a woman has a temp of >38 in labor anf why
Give prophylactic benzylpenecillin to prevent GBS infection
How much weight needs to be lost PP for midwife referral
10 %
Breathlessness and sudden abdomen increase in size, presenting between weeks 16 and 26
Twin to twin transfusion syndrome
1 foetus is a donor which recieves less nutrients and the other becomes fluid overloaded
On USS one foetus will have empty bladder
2 stages of stage 1 of labor
Latent= 0-3cm dilation
Active= 3-10cm
How long can you forget your patch change before consequences
48 hours
Same as COCP
What happens if 2 COC pills are missed in week 3
Omit pill free period
Does hormonal contraception increase risk of breast cancer
Yes
What is the difference between partial and complete hydatiform mole
Complete is when 2 sperm fertilize an empty ovum
Partial is when 2 sperm fertilize a functional ovum
Enlarged and boggy uterus gonad
Adenomyosis
Endometrial tissue growth in muscular wall (myometrium)
Do you get dysmenorrhea in PID and endometriosis
Yes in endometriosis
No in PID
Good way to distinguish
What do you give pregnant women with thrush
Clotrimazole pessary
Oral fluconazole is CI due to risk of congenital abnormality
Which hormone is the best evidence of ovulation
Progesterone
Peaks at day 21
Which blood disease is a CI for expectant Mx of a miscarriage
Von Willebrand Disease
Give misoprostol PV
What’s the best form of contraception for someone taking anti-epileptic drugs
Copper coil
Which contraception is linked with weight loss
Depo injection
Definitely more common to gain weight with it tho
What is the classic presentation of placental abruption vs placenta praevia
Constant lower abdominal pain
woman may be more shocked than is expected by visible blood loss
Tender, tense uterus* with normal lie and presentation.
Fetal heart may be distressed
Placenta praevia= Vaginal bleeding, no pain. Non-tender uterus* but lie and presentation may be abnormal
How do you manage fibroids
Manage the symptoms e.g. if menorrhagia treat the pain
If really big and lots of symptoms consider surgical removal
Consider GnRH analogues to reduce hormonal effects
What is the smear regime if you are HIV positive
Smear every year
Snow storm appearance on obs USS
Complete hydatiform mole
What cancer risks come with COCP
Increases risk of cervical and breast cancer (ones we screen for)
Decreases risk of uterine and ovarian cancer
What is the first line medication for hyeremesis gravidarum
Cyclizine
Which Abx do you prescribe in preterm PROM
Erythromycin
Do you give aspirin in pregnancy
Usually avoided but given in pre-eclampsia
Avoid in breastfeeding
what are the indications for emergency C-section in placenta praevia
active labor
refractory life-threatening maternal hemorrhage
a category III fetal heart rate tracing
significant vaginal bleeding at ≥34+0 weeks of gestation.
How do you manage placenta praevia in outpatients after a bleeding episode
Counseling:
- Avoid excess physical activity, including sexual intercourse
- call their provider promptly if bleeding or labor occurs.
A course of antenatal corticosteroid therapy is administered.
Anti-D immune globulin is administered to RhD-negative patients
Planned C-section at 36/37
What is first line meds in HG and what drug class is it
Promethazine
Antihistamines are first-line in the management of nausea & vomiting in pregnancy/hyperemesis gravidarum
MMR vaccine schedule
1234
12 months, 3-4 years
Loose stool following gastroenteritis
Transient lactose intolerance is a common complication of viral gastroenteritis
How to manage someone on NOACs e.g. apixaban in pregnancy
Switch to heparin e.g enoxaparin
LMWH does not cross the blood brain barrier so is safe in preg
What is the organism that causes GBS
Streptococcus agalacticae is the bacterium which causes Group B Streptococcal disease (GBS)
Breast and endometrial cancer risk in oestrogen and combined HRT
HRT- increased risk of breast cancer
increased by the addition of a progestogen
the risk of breast cancer begins to decline when HRT is stopped and by 5 years it reaches the same level as in women who have never taken HRT
increased risk of endometrial cancer
oestrogen by itself should not be given as HRT to women with a womb
reduced by the addition of a progestogen but not eliminated completely
the BNF states that the additional risk is eliminated if a progestogen is given continuously
Breast, endometrial and ovarian cancer risk in combined/ oestrogen-only HRT
Breast:
- combined= increased risk. Risk reduces when you stop and increases the more you take it
-oestrogen only= slightly increased risk (less than combined), reduces
Ovarian:
- both slightly increase the risk, reduces
Endometrial:
- combined has no effect
- oestrogen only increases the risk (only given when patient has had a hysterectomy)
Specific requirement to be eligible for oestrogen only HRT
Has to have had a hysterectomy
COCP Breast, cervical, ovarian, endometrial cancer risks
Increased risk of breast and cervical cancer (ten years after stopping the risk is back to baseline)
Decreased risk of ovarian and endometrial cancer (stays when stop taking)