GORD Flashcards
Predisposing factors for GORD?
- obesity
- smoking
- alcohol
- large, late meals
Common associated conditions?
- sliding hiatus hernia
- pyloric stenosis
- pregnancy
Uncommon associated conditions?
- diabetic neuropathy
- scleroderma
What mechanisms may be behind GORD?
- raised intra-abdominal pressure, e.g. obesity, eating large meals, tight clothing, pregnancy
- faulty oesophageal sphincter, e.g. pregnancy - due to hormonal smooth muscle relaxation, smoking, fatty meals, hiatus hernia, after surgery for achalasia
- drugs, e.g. tricyclic depressants, anticholinergics which affect the function of the lower oesophageal sphincter
What are the typical symptoms of GORD?
- heartburn
- acid regurgitation
What are the atypical symptoms of GORD?
- dysphagia
- globus sensation
- non-cardiac chest pain
- dyspepsia or abdominal pain
Some extra-oesophageal GORD features?
- hoarseness
- sore throat
- chronic cough
- laryngitis
- polyps on the vocal cords
- dental erosions
When should GORD be investigated?
- atypical symptoms
- dysphagia
- short duration of symptoms in patient over 55 years
- weight loss
How is GORD investigated?
- OGD (can exclude carcinoma)
What features require URGENT referral for OGD?
gastrointestinal bleeding
iron deficiency anaemia
progressive unintentional weight loss
progressive difficulty swallowing
persistent vomiting
epigastric mass on palpation
suspicious barium meal result or other suspicious imaging result
What are some complications of GORD?
severe erosive oesophagitis Barrett's oesophagus oesophageal carcinoma oesophageal stricture haematemesis melaena iron deficiency anaemia
How is GORD managed?
- PPIs