Gonorrhea Flashcards
What Sample Is Needed For Neisseria Gonorrhoeae?
- The best sample for men is the urethral discharge smear.
- Females can make a smear from the vagina.
In females, a cervical smear can also be taken. - An anal canal smear can be taken.
- Smears are made from prostatic secretions, urethra, cervix, and pelvic inflammatory disease.
What Are The Indications For Neisseria Gonorrhoeae?
-A urethral smear is stained to diagnose gonorrhea.
-A cervical smear is stained to diagnose gonorrhea.
-It is advised to diagnose sexually transmitted diseases.
How Will You Define Neisseria Gonorrhea?
-Neisseria is a human pathogen and does not cause infection in animals. So, the spread is through close contact through the sexual route.
-Neisseria is sensitive to drying and does not survive out of the body.
-Neisseria gonorrhoeae causes contagious diseases and is usually sexually transmitted.
-Mother can transmit the disease to the newborn.
The incubation period is
2-10 days
These are _______ parasites of the human urogenital area
obligate
These are characteristically seen in ______ with adjacent sides ______.
pairs; concave
In the purulent material, these are seen ________ and outside the cells.
intracellularly
N. Gonorrhoeae is gram-negative bacteria that can grow in the body, like the
urethra, cervix, uterus, and fallopian tubes in females and the urethra in males
These bacteria grow in
enriched media (Chocolate agar).
Incubation is done in a moist atmosphere containing
5-10% CO2
These media may contain
antibiotics (Lincomycin) to inhibit the growth of other bacteria.
The identification test is
carbohydrate utilization, which produces acid only from glucose
colony morphology
Small gray glistening colonies form after 24 hours of incubation, which may become larger after 48 hours.
There are two pathogenic Neisseria:
N. Gonorrhoeae (Gonococcus).
N. Meningitides (Meningococcus).
N.Gonorrhoeae can infect any epithelium lined by columnar cells with cilia-like:
Urethra.
Cervix.
Rectum.
Pharynx.
Conjunctiva.
But cannot vagina, which is the squamous epithelium.
It grows in the warm, moist area of the female reproductive system.
It can also grow in the mouth, throat, and anus.
Extracellular Gram negative
diplococci
not diagnostic
Intracellular Gram negative
diplococci
diagnostic
Neisseria gonorrhea causes:
Genital infection.
Proctitis.
Oropharyngeal infection.
arthritis.
In the male:
There is a urethral purulent discharge.
There is dysuria.
There may be proctitis and tenesmus.
There is pelvic pain.
In the female:
Females are usually asymptomatic.
Gonorrhea in females is symptomatic in about 75% to 80% and 19% to 15% in males.
There is mucopurulent cervicitis.
There is vaginal discharge.
There may be dysuria.
There may be proctitis.
N. gonorrhea causes gonorrheal urethritis and initiates the majority of cases of acute salpingitis, a so-called pelvic inflammatory disease.
What Type Of Gonorrheal Disease Is Seen In Females?
Urethritis
Conjunctivitis
Vulvitis.
Vaginal discharge.
Swollen lymph nodes.
Bleeding after intercourse.
What Type Of Gonorrheal Disease Is Seen In Males?
Urethritis (burning micturition).
Swollen, painful testes.
Enlarged lymph nodes in the throat.