Gonad Development Flashcards
When does indifferent stage of gonads take place?
4-7 weeks
Indifferent gonads develop in what?
Urogenital ridge (гребень)
The components of Urogenital ridge are?
- primordial germ cells
- primary sex cords
- mesonephric (Wolffian, male) and paramesonephric (Mullerian, female) ducts
Development of testis and male reproductive system is directed by what?
- Sri gene (Y chromosome, encodes testis-determining factor)
- Testosterone (by Leydig cells)
- Mullerian inhibiting factor (by Sertoli cells)
- Dihydrotestosterone (DHT): external henitalia
If there are no factors the fetus will be
female
When does spermatogenesis begin?
After puberty
When does oogenesis begin?
On week 4
What happens when female reach puberty?
Every month Primary oocyte (arrested in P phase of meiosis 1) develops in Secondary Oocyte (arrested in M phase of meiosis 2) which is ovulated
What happens to Secondary oocyte after fertilization?
It completes meiosis 2 and forms mature oocyte and polar body
When are all of the primary oocytes formed?
On 5th month of fetal life