GOLJAN Flashcards
MCC typical community acquired pneumonia
streptoccocus pneumonia
- novobiocin sensitive
MC pathogenesis of pneumonia
microaspiration of oropharyngeal contents during sleep
how does bronchopneumonia begin
bronchitis that extends to the parenchyma
clinical finding in pneumonia
fever - productive cough - chest pain -
DULLNESS TO PERCUSSION
HYPERRESONANCE
causes of ATYPICAL community acquired pneumonia
mycoplasma pneumonia
chlamydophila pneumonia
chlamydia trachomatis in newborns*
RSV, influenza, adenovirus
atypical pneumonia AKA
interstitial pneumonia
signs of atypical pneumonia
low grade fever
non productive cough
chest pain
NO consolidation - free of exudate*
MCC of nosocomial pneumonia
gram + (staph aureus)
gram - (P.aeruginosa + E.coli)
respirators?? pseudomonas
common opportunistic infections in pneumonia
- CMV
- Pneumocystis jiroveci
- Aspergillus fumigatus
where does TB reside once in body?
phagosomes of alveolar macrophages
what is the virulence factor for TB
cord factor
prevents fusion of lysosomes with phagosomes
TB staining
acid fast due to mycolic acid
PPD stands for
purified protein derivative
positive PPD test means
protein in cell wall of TB
** does not distinguish active vs inactive TB
primary TB site
upper part of lower lobes
or lower part of upper lobes
secondary TB site
apical lung
ghon complex/focus
complex-caseous necrosis of hilar lymph nodes
focus-caseous necrosis in periphery
clinical features of TB
fever - night sweat - weight loss
MC extrapulmonary site of TB
kidney
TB to adrenals results in
Addison’s disease
MC TB in AIDS
MAC
mycobacterium avium-intracellulare complex
when does MAC infect in AIDS
when Th count is <50cells/mm3
