GOLJAN Flashcards

1
Q

MCC typical community acquired pneumonia

A

streptoccocus pneumonia

- novobiocin sensitive

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2
Q

MC pathogenesis of pneumonia

A

microaspiration of oropharyngeal contents during sleep

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3
Q

how does bronchopneumonia begin

A

bronchitis that extends to the parenchyma

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4
Q

clinical finding in pneumonia

A

fever - productive cough - chest pain -
DULLNESS TO PERCUSSION
HYPERRESONANCE

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5
Q

causes of ATYPICAL community acquired pneumonia

A

mycoplasma pneumonia
chlamydophila pneumonia
chlamydia trachomatis in newborns*
RSV, influenza, adenovirus

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6
Q

atypical pneumonia AKA

A

interstitial pneumonia

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7
Q

signs of atypical pneumonia

A

low grade fever
non productive cough
chest pain
NO consolidation - free of exudate*

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8
Q

MCC of nosocomial pneumonia

A

gram + (staph aureus)
gram - (P.aeruginosa + E.coli)

respirators?? pseudomonas

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9
Q

common opportunistic infections in pneumonia

A
  1. CMV
  2. Pneumocystis jiroveci
  3. Aspergillus fumigatus
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10
Q

where does TB reside once in body?

A

phagosomes of alveolar macrophages

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11
Q

what is the virulence factor for TB

A

cord factor

prevents fusion of lysosomes with phagosomes

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12
Q

TB staining

A

acid fast due to mycolic acid

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13
Q

PPD stands for

A

purified protein derivative

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14
Q

positive PPD test means

A

protein in cell wall of TB

** does not distinguish active vs inactive TB

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15
Q

primary TB site

A

upper part of lower lobes

or lower part of upper lobes

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16
Q

secondary TB site

A

apical lung

17
Q

ghon complex/focus

A

complex-caseous necrosis of hilar lymph nodes

focus-caseous necrosis in periphery

18
Q

clinical features of TB

A

fever - night sweat - weight loss

19
Q

MC extrapulmonary site of TB

A

kidney

20
Q

TB to adrenals results in

A

Addison’s disease

21
Q

MC TB in AIDS

A

MAC

mycobacterium avium-intracellulare complex

22
Q

when does MAC infect in AIDS

A

when Th count is <50cells/mm3