Goljan Flashcards
What do we find in lab. for pre/eclampsia? BUN Uric Acid Serum Creatinine GFR transaminases
BUN increased uric acid increased creatinine increased GFR decreased transaminases increased Schistocytes/anemia/thrombocytopenia
Should GFR be increased or decreased in normal pregnancy?
Increased
Should BUN be increase or decreased in normal pregnancy?
decreased in normal pregnancy
What is the clinical picture of eclampsia?
same as pre-eclampsia but w/ seizures or convulsions
What is the clinical presentation of pre-eclampsia?
hypertension proteinuria pitting edema
Tx for Eclampsia?
Magnesium Sulfate
What two substances are vasodilators in pre-eclampsia?
PGE1 N.O.
What are two substances in pre-eclampsia that are vasoconstrictors?
Angiotensin II TXA2
What substances are decrease in pre-eclampsia?
PGE1 and NO
What two substances are increased in pre-eclampsia?
Angiotensin II TXA2
What is the Diagnosis if pregnant woman presents w/ pre-eclampsia in first trimester?
hydatidiform mole
When does pre-eclampsia and eclampsia occur? trimester…
3rd trimester
What organism causes chorioamnionitis?
Step. agalactiae
What part of the eye is affected w/ Kayser-Fleischer rings?
outer part of decemet cornea
What are the symptoms of degeneration of the lenticular nuclei?
- chorea - rigidity - basal ganglia dementia
What nuclei is attacked in Wilson’s Dz?
lenticular nuclei degeneration
What is the Tx of Wilson’s Dz?
penicillamine
What are some of the clinical manifestations of Wilson’s Dz?
Kayser-Fleishcher rings in eye
What is ceruloplasmin?
protein that binds to Copper low ceruloplasmin so can’t bind Copper - so increase of Cu in blood
What is Wilson’s Dz?
defect in Copper (Cu+) secretion into bile - bile is Copper deficient or - defect in synthesis of ceruloplasmin
What is the Tx of hemochromatosis?
phlebotomy
What are the manifestations of hemochromatosis?
- bronze skin
What is the best screening test?
increase serum ferritin
What are the laboratory findings of hemochromatosis?
- increase serum iron - decrease TIBC - increase % saturation - increase serum ferritin