Goitre simple Flashcards

1
Q

Def d’un goitre simple:

A
  • hypertrophie de la thyroïde indolore,
  • non compressive
  • sans dysthyroidie
  • sans étiologie sous jacente
  • sans nodule associé
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2
Q

signe clinique:

A
  • pas de signe clinique
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3
Q

Biologie + imagerie:

A
  • normale
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4
Q

TSH augmentée/ normale ou baissée ?

A
  • pas d’augmentation de la TSH

mais augmentation de la sensibilité du parenchyme thyroïdien à la TSH

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5
Q

fréq:

A
  • 5-10 % de la population

- fille > garçon

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6
Q

FDR: carence en quoi ?

A
  • carence iodées
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7
Q

FDR: quels aliments ?

A
  • manioc

- rutabaga..

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8
Q

FDR: génétique ?

A
  • prédisposition génétique
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9
Q

FDR: hormones ?

A
  • chez le femme enceinte -> favorise la goitrigénèse + croissance des nodules
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10
Q

FDR: tabac ?

A
  • thyocyanate est un compétiteur de l’iode
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11
Q

FDR: quels médicaments

A
  • lithium

- IFN

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12
Q

évolution:

A
  • goitre homogène (adolescent) -> paucinodulaire -> multinodulaire asymptomatique, puis symptomatique -> multinodulaire compliqué (au-dela de 50 ans)
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13
Q

complications:

A
  • hyperthyroïdie
  • inflammation
  • hematocèle (irruption brutale de sang au sein d’un nodule)
  • compression
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14
Q

le goitre simple est-il FDR de cancer ?

A
  • non
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15
Q

T:

A
  • de la carence
  • des facteurs favorisants
  • levothorax (T4 synthétic)
  • prise en charge des nodules si goitre nodulaire (chirurgie, IRA thérapie)
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