Glycolysis Pay Off Flashcards

1
Q

What is glycolysis?

A

Glycolysis is the metabolic pathway that converts glucose into pyruvate, producing ATP and NADH in the process.

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2
Q

True or False: Glycolysis occurs in the mitochondria of the cell.

A

False: Glycolysis occurs in the cytoplasm of the cell.

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3
Q

What is the net gain of ATP from one molecule of glucose during glycolysis?

A

The net gain is 2 ATP molecules.

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4
Q

What are the two main phases of glycolysis?

A

The two main phases are the energy investment phase and the energy payoff phase.

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5
Q

Fill in the blank: The energy payoff phase of glycolysis produces _____ and _____ molecules.

A

ATP and NADH

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6
Q

What is the role of NAD+ in glycolysis?

A

NAD+ serves as an electron carrier, being reduced to NADH during glycolysis.

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7
Q

Which enzyme catalyzes the conversion of glucose to glucose-6-phosphate?

A

Hexokinase

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8
Q

What is the primary purpose of the energy investment phase?

A

To invest ATP to phosphorylate glucose and its intermediates, preparing them for subsequent reactions.

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9
Q

True or False: Glycolysis does not require oxygen.

A

True: Glycolysis is an anaerobic process.

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10
Q

What is produced at the end of glycolysis from one glucose molecule?

A

Two pyruvate molecules.

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11
Q

In glycolysis, how many molecules of ATP are consumed in the energy investment phase?

A

2 ATP molecules.

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12
Q

What is the final electron acceptor in glycolysis?

A

Pyruvate.

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13
Q

Multiple Choice: Which of the following is NOT a product of glycolysis? A) ATP B) NADH C) Acetyl-CoA D) Pyruvate

A

C) Acetyl-CoA

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14
Q

What happens to pyruvate in the absence of oxygen after glycolysis?

A

It undergoes fermentation to produce lactate or ethanol.

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15
Q

What is the function of phosphofructokinase in glycolysis?

A

It is a key regulatory enzyme that converts fructose-6-phosphate to fructose-1,6-bisphosphate.

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16
Q

True or False: Glycolysis produces more ATP than it consumes.

A

True: Glycolysis produces a net gain of ATP.

17
Q

What is the total yield of NADH from one molecule of glucose during glycolysis?

A

2 NADH molecules.

18
Q

Fill in the blank: The enzyme _____ catalyzes the conversion of phosphoenolpyruvate to pyruvate, producing ATP.

A

pyruvate kinase

19
Q

What is the significance of substrate-level phosphorylation in glycolysis?

A

It is the process by which ATP is produced directly from a phosphorylated intermediate.

20
Q

How many total ATP molecules are produced during glycolysis before considering the investment phase?

A

4 ATP molecules.

21
Q

What are the three main stages of glycolysis?

A

Energy investment, cleavage, and energy payoff.

22
Q

True or False: Glycolysis is a reversible process.

A

False: Glycolysis is largely irreversible under physiological conditions.

23
Q

Which glycolysis intermediate is split into two three-carbon molecules?

A

Fructose-1,6-bisphosphate.

24
Q

What does the term ‘anaerobic’ mean in the context of glycolysis?

A

It means that the process does not require oxygen.

25
In glycolysis, what is the effect of high ATP levels on phosphofructokinase activity?
High ATP levels inhibit phosphofructokinase activity, slowing down glycolysis.
26
What are the end products of glycolysis under aerobic conditions?
Pyruvate, ATP, and NADH.