Glycolysis Flashcards

1
Q

What are the two processes that make up metabolism?

A

catabolism

anabolism

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2
Q

d: metabolism

A

the chemical processes that occur within a living organism in order to maintain life

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3
Q

d: anabolism

A

the synthesis of complex molecules in living organisms from simpler ones together with the storage of energy; constructive metabolism

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4
Q

d: catabolism

A

the breakdown of complex molecules in living organisms to form simpler ones, together with the release of energy; destructive metabolism.

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5
Q

is anabolism oxidative/reductive and exergonic/endergonic?

A

reductive and endergonic

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6
Q

What carbohydrate is our primary energy source?

A

glucose

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7
Q

What is oxidation of glucose through aerobic glycolysis used for?

A

pyruvate

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8
Q

What is glucose produced by fermentation of anaerobic glycolysis used for?

A

lactate

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9
Q

What is oxidation through the pentose phosphate pathway used for?

A

ribose-5-phosphate

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10
Q

what is excess glucose produced used for?

A

storage

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11
Q

why cant glucose be stored as glucose?

A

as metabolises too fast so cant be stored

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12
Q

How does glucose get into the cell?

A

via facilitated diffusion via GLUTs

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13
Q

what are the 2 major cellular needs of glucose?

A

production of ATP

provision of building blocks for synthetic reactions

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14
Q

What are the 3 control points in glycolysis?

A

hexokinase
phosphofructokinase
pyruvate Kinase

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15
Q

what enzyme controls the rate of substrate movement?

A

phosphofructokinase

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16
Q

d: The Warburg Effect

A

the observation that even in aerobic conditions, cancer cells tend to favour metabolism via glycolysis

17
Q

Why do cancer patients lose weight?

A

Very inefficient ATP synthesis
High glucose consumption demand
Cancer patients lose weight