Glycolysis

Question 1

What is the first step of Glycolysis?

Answer 1

Hexokinase uses 1 ATP to add a phosphate to Glucose, forming Glucose-6-Phosphate

Question 2

Why is a Phosphate added to Glucose?

Answer 2

To trap Glucose in the cell and destabilise it for further breakdown.

Question 3

What is the Second step of Glycolysis?

Answer 3

Phosphoglucoseisomerase converts Glucose-6-Phosphate to Fructose-6-Phosphate

Question 4

Why is G-6-P Converted into F-6-P?

Answer 4

To prepare the sugar for cleavage, which requires a ketose (F-6-P) and not an aldose (G-6-P)

Question 5

What is The Third Step of Glycolysis?

Answer 5

Phosphofructokinase uses 1 ATP to convert Fructose-6-Phosphate to Fructose 1,6 Biphosphate

Question 6

Why is Phosphofructokinase a key regulator of Glycolysis?

Answer 6

Because it is an irreversible reaction that “locks” glucose into glycolysis.

Question 7

What happens after F 1,6 BP is produced?

Answer 7

Glycolysis pathway splits Fructose 1,6 Biphosphate (6C) into x2 3 Carbon molecules.