Glycolysis

Question 1

Glycolysis overview (6 carbon molecule, reaction)

Answer 1

• A 6 carbon molecule (glucose) is split into a 3 carbon molecule called pyruvate
• There is a total of 10 reactions, which are controlled by enzymes

Question 2

End results of glycolysis

Answer 2

• Net 2 ATP (4 are produced, but 2 are uder at the beginning)
• 2 NADH
• 2 pyruvate

Question 3

Reactions 1-5 (investment)

Answer 3

1. ATP phosphorylates to glucose forming G6P
2. G6P is rearranged to form F6P
3. ATP phosphorylates to F6P forming F1 and 6-BP
   4-5. F1 and 6-BP split to form DHAP AND G3P (DHAP is immediately converted into G3P, you you’ll get 2 G3P molecules)

During this phase 2 ATP molecules are used

Question 4

Reactions 6-10 (“Pay-Off”)

Answer 4

6. Two G3P molecules are converted to BPG. During the process H+ are removed from G3P, which are used to reduce NAD+ to NADH
7. BPG is converted to 3PG. A phosphate group on BPG phosphorylates with ADP forming ATP
8. 3PG is rearranged into 2PG
9. 2PG is converted into PEP by the removal of water
10. PEP is converted to pyruvate. A phosphate group on PEP phosphorylates with ADP to form ATP