Glycogen Synthesis

Question 1

How is a glycogen chain made?

Answer 1

1- start with protein primer glycogenin
2- udp with glucose attached comes along and slides its glucose off to attach to the primer
3-chain carries on

Question 2

What enzyme is switched off via phosphorylation?

Answer 2

Glycogen synthase, occurs via protein kinase

Question 3

What enzyme is inhibited by insulin

Answer 3

Glycogen synthase

Question 4

What is an allosteric activator of glycogen phosphorylase?

Answer 4

Amp

Question 5

Whats the disease that causes a mutation on glucose 6 phosphate and what are the symptoms?

Answer 5

Von gierke

Enlarged liver, hypoglycaemia

Question 6

What’s the disease that causes a mutation in lysosomal glycosidase and what are the symptoms?

Answer 6

Pompes, muscle weakness/fatigue

Question 7

What’s the disease that causes a mutated glygocen phosphorylase and what are the symptoms?

Answer 7

Mcardles, exercise intolerance