Glycogen Metabolism

Question 1

The hormone insulin favors glycogen synthesis by which one of the following mechanisms?
A. Promoting the dephospho form of glycogen synthase
B. Promoting the phospho form of glycogen synthase
C. Promoting the phospho form of glycogen phosphorylase
D. Inhibiting the insulin receptor
E. Activating glycogen synthase kinase

Answer 1

A. Promoting the dephospho form of glycogen synthase

Question 2

A 10-year-old boy complains of muscle cramping following mild exercise. Laboratory tests reveal a muscle enzyme deficiency and elevated muscle glycogen with normal structure. Which of the following enzymes is most probably deficient in this boy?
A. alpha-(1,6)-glucosidase
B. glucosyl (4,6) transferase
C. Glycogen synthase
D. Glucose 6-phosphatase
E. Glycogen phosphorylase

Answer 2

E. Glycogen phosphorylase