Glycogen and fat

Question 1

Name 4 cells with an absolute requirement for glucose

Answer 1

1. RBC
2. neutrophils
3. Innermost cells of kidney medulla
4. lens of the eye

Question 2

What store enables glucose to be kept at a constant level?

Answer 2

Glycogen stores

Question 3

At 2.8mmol/l of glucose, how would the patient appear?

Answer 3

confused

Question 4

What is a normal blood glucose level

Answer 4

5mmol/l

Question 5

If blood glucose is chronically high (8mmol) what are common physiological consequences for a diabetic?

Answer 5

Retinopathy
Neuropathy
Foot ulcers

Question 6

2major stores of glycogen in the body?

Answer 6

Muscle and liver

Question 7

Why can glycogen in muscles not be used to replenish glucose levels?

Answer 7

It remains in the muscle

Question 8

Which bonds form branches/ chains in glucose?

Answer 8

Branches = a 1-6 glycosidic
Chains = a 1-4 glycosidic

Question 9

What role does glycogenin play in glucose structure?

Answer 9

chains originate from glycogenin (acts as a primer at core of glycogen structure)

Question 10

What is the function of glycogenesis?

Answer 10

synthesis of glycogen

Question 11

Which enzymes create branches/ chain in glycogen?

Answer 11

branches - a 1-6 branching enzyme

chain - a 1-4 - glycogen synthase