Glucose Stuff Flashcards
The oxidative phase of the Pentose Phosphate Pathway generates…
NADPH (2 per G6P) and ribulose (1 per G6P)
Key enzyme in the oxidative phase of the Pentose Phosphate Pathway
glucose-6-P dehydrogenase
What pathway is the only source for NADPH for RBCs?
PPP
The nonoxidative phase of the PPP genereates different sugars including
Ribose-5-P
Transaldolase transfers how many keto units
3C keto units
transketolase transfers how many keto units
2C keto units
Transketolase needs what to function properly
TPP (thiamine dependent enzyme)
Transaldolase uses ______ for nucleophilic attack on aldehyde
Lysine
The most common known enzyme deficiency
Glucose 6-P DH deficiency
denatured Hemoglobin precipitates within RBCs due to oxidative stress
Heinz Bodies
NADPH is neceessary to keep ______ reduced
glutathione
fructokinase deficiency
Fructosuria
Aldolase B deficiciency
Fructosemia