Glucopeptidos, lipopetidos y oxozalidinas Flashcards

1
Q

Mecanismo de los glucopeptidos

A

bactericidas, actuan en la pared de peptidoglucano en la D-ala-D-ala-transpeptidasa

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2
Q

Cuales son los glucopéptidos

A

vancomicina, teomicina, daptamicina, oritomicina, telavancina

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3
Q

Via de excrecion de glucopeptidos

A

renal

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4
Q

Embarazo?

A

No, riesgo/beneficio

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5
Q

Efectos adversos en general de los glucopeptidos

A

Sindrome del hombre rojo, mielotoxicidad, nefrotoxicidad, ototoxicidad, fleblitis, necrosis, px en quimio terapia

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6
Q

Cobertura de los glucopeptidos

A

cocos +: estrepto, msra, enterococos,
anaerobios gram +: peptoestreptocoos
Bacilos +: clostridium

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7
Q

Via de administracion glucopeptidos

A
Vanco: vo y ev
Teico: im y ev
Orito: ev
Dalba: EV
tela: ev
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8
Q

Indicacion de vancomicina

A

2da linea para tratamiento de diarrea por atb
ATB de eleccion para endocarditis + gentamicina
osteomelitis
neumonia nosocomial
IPTB

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