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BIOCHEM PREFINALS > Gluconeogenesis > Flashcards

Gluconeogenesis Flashcards

1
Q

Step 1
Substrate
Enzyme
Product
Hormone

A

Carboxylation
Pyruvate
Pyruvate carboxylase (biotin-dependent) Oxaloacetate
Glucagon, Cortisol

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2
Q

Step 2
Substrate
Enzyme
Product

A

Decarboxylation & Phosphorylation
Oxaloacetate
Phosphoenolpyruvate carboxykinase (PEPCK) Phosphoenolpyruvate (PEP)

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3
Q

Step 3
Substrate
Enzyme
Product

A

Hydration
PEP
Enolase
2-Phosphoglycerate

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4
Q

Step 4
Substrate
Enzyme
Product

A

Isomerization
2-Phosphoglycerate
Phosphoglycerate mutase
3-Phosphoglycerate

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5
Q

Step 5
Substrate
Enzyme
Product

A

ATP consumption
3-Phosphoglycerate
Phosphoglycerate kinase
1,3-Bisphosphoglycerate

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6
Q

Step 6
Substrate
Enzyme
Product

A

Reduction
1,3-Bisphosphoglycerate
Glyceraldehyde-3-phosphate dehydrogenase
Glyceraldehyde-3-phosphate (G3P)

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7
Q

Step 7
Substrate
Enzyme
Product

A

Isomerization
DHAP
Triose phosphate isomerase
G3P

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7
Q

Step 8
Substrate
Enzyme
Product

A

Condensation
G3P, G3P
Aldolase
Fructose-1,6-bisphosphate

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8
Q

Step 9
Substrate
Enzyme
Product

A

Dephosphorylation (Bypass)
Fructose-1,6-bisphosphate
Fructose-1,6-bisphosphatase
Fructose-6-phosphate

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9
Q

Step 10
Substrate
Enzyme
Product

A

Isomerization
Fructose-6-phosphate
Phosphohexose isomerase
Glucose-6-phosphate

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10
Q

Step 11
Substrate
Enzyme
Product

A

Dephosphorylation (Bypass)
Glucose-6-phosphate
Glucose-6-phosphatase
Glucose

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BIOCHEM PREFINALS (7 decks)

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