GLP1a

Question 1

GLP1a Cautions?

Answer 1

Severe GI disease
W/ sulfonylureas
Renal

Question 2

GLP1a Doses:

Answer 2

Exetanide(byetta)=>5bd-10bd

Lira-glutide(victoza)=> .6mg-1.8

Question 3

GLP1a Counselling?

Answer 3

Exetanide: 1h before 2 main meals 6hr apart
Tell dr if severe abdominal pain
If affcted by n/v/diarr drink plenty fluid
Slows gastric emptying thus anyibiocs 1hr b4 or 4hr after

Weekly bydureon- same day weekly

Question 4

GLP1a Side effects??

Answer 4

N/v
Diarrhoea
Abd pain
Injection site reaction
Hygpog
(Anything GI)

Question 5

What is Glucagon like peptide 1 analogue MOA? (GLP1a)

Answer 5

• Increase glucose-dep insulin secretion
• Supp inap glucagon secretion
• Delays gastric emptying(slows gluc abs and reduces apetite)

(Deep, therefore 3 actions–> inj)