Glossary

Question 0

Bleeding disorder due to deficiency of a particular coagulation factor

Answer 0

Hemophilia

Question 1

These are antibodies characterized as weak and can be diluted to high titer despite the weak reaction strengths.

Answer 1

High Titer Low Aviditity HTLA

Question 2

Factor VIII deficiency mostly for males

Answer 2

Hemophilia A

Question 3

AKA Christmas disease. Due to absence of FActor IX

Answer 3

Hemophilia B

Question 4

Low RBC count resulting from destruction of circulating erythrocytes.

Answer 4

Hemolytic anemia

Question 5

Condition in which a patient has shortened red blood cell survival associated with hemolysis mediated by humoral anti body.

Answer 5

Immune Hemolytic Anemia

Question 6

Continuous red blood cell destruction resulting to anemia due to the presence of autoantibodies directed against the patients own red blood cells.

Answer 6

Autoimmune hemolytic anemia

Question 7

It is the red blood cell destruction due to drug induced production of an autoantibody that recognizes red blood cell antigen

Answer 7

Drug induced hemolytic anemia

Question 8

Red blood cell destruction due to the presence of alloantibodies to foreign red cell antigens introduced to the circulation through transfusion or pregnancy

Answer 8

Alloimmune hemolytic anemia

Question 9

An increase in the volume of blood plasma resulting to reduced concentration of red blood cells

Answer 9

Hemodilution

Question 10

it is a plasma protein which binds to hemoglobin following intravascular hemolysis

Answer 10

Haptoglobin

Question 11

a very small substance to stimulate antibody production without attaching to a larger molecule

Answer 11

Hapten

Question 12

These are genes that are close on the chromosome and inherited together by an individual

Answer 12

haplotype

Question 13

condition characterized by markedly decreased leukocytes in the blood

Answer 13

Granulocytopenia

Question 14

Intense and frequently fatal immunologic reaction of engrafted cell against the host caused by the infusion of immunocompentent lymphocytes into individuals with impaired immunity

Answer 14

Graft vs Host disease GVHD

Question 15

Unit of inheritance within the chormosome

Answer 15

Gene

Question 16

A pair of gene in which neither is dominant over the other, that is, they are bothh expressed.

Answer 16

codominant

Question 17

A gene that does not appear to produce a detectable antigen

Answer 17

Amorphic

Question 18

One of two or more different genes that may occupy a specific locus on a chromosome

Answer 18

Allelic

Question 19

A gene that expressed if present

Answer 19

Dominant

Question 20

A gene which is not expressed unless it is in the homozygous form

Answer 20

Recessive

Question 21

A gene that produces a repressor substance that inhibits an operator gene

Answer 21

Regulatory

Question 22

A gene that suppresses the phenotypic expression of another gene

Answer 22

Supressor

Question 23

Specific place on the chromosome where a gene is located

Answer 23

Gene locus

Question 24

It is a persons genetic make up

Answer 24

Genotype

Question 25

The genetic state of having two similar genes for the same trait

Answer 25

Homozygous

Question 26

The genetic state of having two dissimilar genes for the same trait.

Answer 26

Heterozygous

Question 27

A cryoprotective agent

Answer 27

Glycerol

Question 28

A process of adding glycerol to a red blood cell unit to prevent hemolysis of erythrocytes while freezing

Answer 28

Glycerolization

Question 29

A carbohydrate attached lipid

Answer 29

Glycolipid

Question 30

Any of several related protein that cN project through the thickness of the cell membrane of erythrocytes

Answer 30

Glycophorin

Question 31

A molecule that consist a carbohydrate and a protein

Answer 31

Glycoprotein

Question 32

A sphingolipid containing the sugar glucose or galactose

Answer 32

Glycosphingolipid

Question 33

An enzyme needed to attach a specific sugar molecule to a predetermined acceptor molecule

Answer 33

Glycosyl transferase

Question 34

One of the five types of immunoglobulin known to be involved in immunity, produced during the second immune response.

Answer 34

Gamma globulin

Question 35

A type of large glycoprotein that is found on the surface of cells and mediates cellular adhesion

Answer 35

Fibronectin

Question 36

The process of dissolving fibrin due to the action of fibrolysin

Answer 36

Fibrolysis

Question 37

Also referred to as plasmin, substance that has the ability to dissolve fibrin.

Answer 37

Fibrinolysin

Question 38

A filamentous clot formed by the action of thrombin fibrinogen

Answer 38

Fibrin

Question 39

Refers to the transplacental passage of fetal blood into the circulation of the maternal organism

Answer 39

Fetomaternal hemorrhage

Question 40

A transfusion reaction caused by leukoagglutinins characterized by fever

Answer 40

Febrile reaction

Question 41

Refers to the activity where a person is likely to get foreign substance, in blood bank practice, this refers to either through blood transfusion or pregnancy

Answer 41

Exposure

Question 42

Refers to the replacement of an infants coated rbc with donor blood until one or two total blood volumes are accomplish

Answer 42

Exchange transfusion

Question 43

An immunologic incompatibility between mother and fetus that can be produce severe or fatal consequences to the unborn or newborn infant due to the destuction of rbcs, is also known as HYDROPS FETALIS

Answer 43

Erythroblastosis fetalis HDN

Question 44

A process whereby cells that are coated with antibody are treated in such manner as to disrupt the bonds between the antigen and antibody

Answer 44

Elution

Question 45

The product of deliberate manipulation of a red cell suspension to break an immune complex with subsequent release of the antibody into e surrounding medium

Answer 45

Eluate