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Glossary Flashcards

0
Q

Bleeding disorder due to deficiency of a particular coagulation factor

A

Hemophilia

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1
Q

These are antibodies characterized as weak and can be diluted to high titer despite the weak reaction strengths.

A

High Titer Low Aviditity HTLA

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2
Q

Factor VIII deficiency mostly for males

A

Hemophilia A

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3
Q

AKA Christmas disease. Due to absence of FActor IX

A

Hemophilia B

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4
Q

Low RBC count resulting from destruction of circulating erythrocytes.

A

Hemolytic anemia

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5
Q

Condition in which a patient has shortened red blood cell survival associated with hemolysis mediated by humoral anti body.

A

Immune Hemolytic Anemia

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6
Q

Continuous red blood cell destruction resulting to anemia due to the presence of autoantibodies directed against the patients own red blood cells.

A

Autoimmune hemolytic anemia

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7
Q

It is the red blood cell destruction due to drug induced production of an autoantibody that recognizes red blood cell antigen

A

Drug induced hemolytic anemia

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8
Q

Red blood cell destruction due to the presence of alloantibodies to foreign red cell antigens introduced to the circulation through transfusion or pregnancy

A

Alloimmune hemolytic anemia

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9
Q

An increase in the volume of blood plasma resulting to reduced concentration of red blood cells

A

Hemodilution

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10
Q

it is a plasma protein which binds to hemoglobin following intravascular hemolysis

A

Haptoglobin

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11
Q

a very small substance to stimulate antibody production without attaching to a larger molecule

A

Hapten

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12
Q

These are genes that are close on the chromosome and inherited together by an individual

A

haplotype

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13
Q

condition characterized by markedly decreased leukocytes in the blood

A

Granulocytopenia

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14
Q

Intense and frequently fatal immunologic reaction of engrafted cell against the host caused by the infusion of immunocompentent lymphocytes into individuals with impaired immunity

A

Graft vs Host disease GVHD

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15
Q

Unit of inheritance within the chormosome

A

Gene

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16
Q

A pair of gene in which neither is dominant over the other, that is, they are bothh expressed.

A

codominant

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17
Q

A gene that does not appear to produce a detectable antigen

A

Amorphic

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18
Q

One of two or more different genes that may occupy a specific locus on a chromosome

A

Allelic

19
Q

A gene that expressed if present

A

Dominant

20
Q

A gene which is not expressed unless it is in the homozygous form

A

Recessive

21
Q

A gene that produces a repressor substance that inhibits an operator gene

A

Regulatory

22
Q

A gene that suppresses the phenotypic expression of another gene

A

Supressor

23
Q

Specific place on the chromosome where a gene is located

A

Gene locus

24
Q

It is a persons genetic make up

A

Genotype

25
Q

The genetic state of having two similar genes for the same trait

A

Homozygous

26
Q

The genetic state of having two dissimilar genes for the same trait.

A

Heterozygous

27
Q

A cryoprotective agent

A

Glycerol

28
Q

A process of adding glycerol to a red blood cell unit to prevent hemolysis of erythrocytes while freezing

A

Glycerolization

29
Q

A carbohydrate attached lipid

A

Glycolipid

30
Q

Any of several related protein that cN project through the thickness of the cell membrane of erythrocytes

A

Glycophorin

31
Q

A molecule that consist a carbohydrate and a protein

A

Glycoprotein

32
Q

A sphingolipid containing the sugar glucose or galactose

A

Glycosphingolipid

33
Q

An enzyme needed to attach a specific sugar molecule to a predetermined acceptor molecule

A

Glycosyl transferase

34
Q

One of the five types of immunoglobulin known to be involved in immunity, produced during the second immune response.

A

Gamma globulin

35
Q

A type of large glycoprotein that is found on the surface of cells and mediates cellular adhesion

A

Fibronectin

36
Q

The process of dissolving fibrin due to the action of fibrolysin

A

Fibrolysis

37
Q

Also referred to as plasmin, substance that has the ability to dissolve fibrin.

A

Fibrinolysin

38
Q

A filamentous clot formed by the action of thrombin fibrinogen

A

Fibrin

39
Q

Refers to the transplacental passage of fetal blood into the circulation of the maternal organism

A

Fetomaternal hemorrhage

40
Q

A transfusion reaction caused by leukoagglutinins characterized by fever

A

Febrile reaction

41
Q

Refers to the activity where a person is likely to get foreign substance, in blood bank practice, this refers to either through blood transfusion or pregnancy

A

Exposure

42
Q

Refers to the replacement of an infants coated rbc with donor blood until one or two total blood volumes are accomplish

A

Exchange transfusion

43
Q

An immunologic incompatibility between mother and fetus that can be produce severe or fatal consequences to the unborn or newborn infant due to the destuction of rbcs, is also known as HYDROPS FETALIS

A

Erythroblastosis fetalis HDN

44
Q

A process whereby cells that are coated with antibody are treated in such manner as to disrupt the bonds between the antigen and antibody

A

Elution

45
Q

The product of deliberate manipulation of a red cell suspension to break an immune complex with subsequent release of the antibody into e surrounding medium

A

Eluate

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