Glomerulus Flashcards

0
Q

What is the equation for GFR

A

GFR=Ui x V /Pi

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1
Q

Why measure glomerular filtration rate?

A

Estimate of how efficiently the kidneys are working, shows severity of kidney disease and used to dictate how much of certain drugs can be prescribed.

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2
Q

Factors effecting filtration rate.

A

Capillary hydrostatic pressure, direct to GFR
Colloid osmotic pressure, inverse to GFR
Bowmans space pressure, inverse to GFR

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3
Q

Layers of glomerular filter

A

Capillary endothelial cells, fenestrated
Basement membrane, negatively charged glycoproteins repel anionic proteins
Podocytes, slit pores

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