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Renal > Glomerulonephritis > Flashcards

Glomerulonephritis Flashcards

1
Q

What symptoms represent those of a nephritic syndrome?

A

Haematuria (with red cell casts)

Hypertension

Oligouria

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2
Q

What signs and symptoms represent the triad of a nephrotic syndrome?

A

Hypoalbuminaemia

Proteinuria

Oedema

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3
Q

What glomerulonephritis does the following biopsy report describe?

Mesangial hypercellularity
Positive immunofluorescence for IgA and C3

A

IgA nephropathy

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4
Q

What glomerulonephritis does the following biopsy report describe?

Endothelial proliferation with neutrophils
Immunofluorescence reveals granular ‘starry sky’ appearance

Electron microscopy: subepithelial ‘humps’ caused by lumpy immune complex deposits

A

Post-streptococcal GN

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5
Q

What GN occurs in the days following an infection?

A

IgA nephropathy

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6
Q

What GN occurs weeks following an infection?

A

Post-streptococcal GN

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7
Q

A patient develops an AKI very quickly and is associated with haemoptysis. What GN is the likely cause?

A

Anti-GBM (Goodpasture’s) disease

Associated with lung haemorrhage and AKIs which onset very suddenly.

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8
Q

The presence of “crescents” on renal biopsy indicates what type of GN?

A

Rapidly progressive GN

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9
Q

What glomerulonephritis does the following biopsy report describe?

No change on light microscopy.
Effacement of podocyte foot processes on electron microscopy.

A

Minimal change disease

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10
Q

What GN is associated with NSAID, lithium or rifampicin use, as well as Hodgkin’s lymphoma.

A

Minimal change disease

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11
Q

What GN is associated with HIV, heroin, lithium and lymphoma?

A

Focal segmental glomerulosclerosis

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12
Q

What GN does the following renal biopsy describe?

Focal and segmental sclerosis and hyalinosis on light microscopy

A

Focal segmental glomerulosclerosis

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13
Q

What GN is associated with anti-phospholipase A2 receptor (PLA2R) antibodies?

A

Membranous nephropathy

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14
Q

What GN does the following renal biopsy describe?

Diffusely thickened GBM with subendothelial deposits.
Subepithelial spike and dome appearance on silver stain

A

Membranous nephropathy

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15
Q

What GN does the following renal biopsy describe?

Subendothelial and mesangial electron dense immune deposits with tram-track appearance

A

Membranoproliferative GN

Immune-complex associated subtype

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16
Q

What GN does the following renal biopsy describe?

Intramembranous immune complexes with “dense deposits”

A

Membranoproliferative GN

C3 subtype

17
Q

What 4 nephropathies present as nephritic syndromes?

A

IgA nephropathy
Post-streptococcal GN
Rapidly progressive GN
Anti-GBM disease (Good pasture’s)

18
Q

What 4 nephropathies present as nephrotic syndromes?

A

Focal segmental glomerulosclerosis
Minimal change disease
Membranous GN
Membranoproliferative GN

Renal (4 decks)

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