Glomerular Filtration Tests Flashcards
TRUE OR FALSE
Glomerular filtration test is NOT a valuable detector for early renal disease.
TRUE
Generally considered the best overall indicator of the level of kidney function
Glomerular filtration rate (GFR)
Clearance test is the _____________ test used to measure the _____________ of the _____________.
Clearance test is the STANDARD test used to measure the FILTERING CAPACITY of the GLOMERULI.
Greatest source of error in any clearance procedure using urine is
Improperly timed specimen
Inulin test is the
Gold standard for exogenous clearance test
Inulin is
not reabsorbed nor secreted by the tubules
This exogenous clearance test is valuable to measure the viability of a transplanted kidney
Radionucleotides
Solution or reagent used in Radionucleotides
Iothalamate/ 125 Iodine
Does Radionucleotide requires to collect urine for the test?
No.
Cons of Radionucleotide
Exogenous procedure
labor intensive
Costly
Earliest glomerular filtration test
UREA
They are for clearance test and for tubular integrity
Cystatin C and Beta 2 microglobulin
Cystatin C is a Small protein produced by all _____________ cells , filtered then reabsorbed and _____________ by
RTE.
Cystatin C is a Small protein produced by all NUCLEATED cells , filtered then reabsorbed and BROKEN DOWN by
RTE.
This reduces production of Cystatin C
Glucocorticoids (steroids)
Beta 2 Microglobulin is high in
LYMPHOCYTES
Beta 2 Microglobulin is not reliable for patient who has
Immune disorders
Drugs that interferes and inhibit creatinine secretion
Gentamicin, cephalosporins and cimetidine
True or False
Creatinine test has DIETARY restrictions
False
Normal value of creatinine in MALE and FEMALE
Male: 107-139 mL/min
Female: 87-107 mL/min
low molecular weight glycoprotein that functions as prostaglandin D synthase
Beta trace protein
What does the MDRD (Modification of Diet in Renal Disease) require?
Age
Sex
Ethnicity
