Global Health Flashcards
What is the leading cause of preventable blindness?
Trachoma
What serological variants of Chlamydia cause trachoma?
A-C
What is the vector for spread of trachoma?
Bazaar fly
What are the signs/symptoms of the acute inflammatory phase of trachoma?
follicular conjunctivitis
vascularisation of superior cornea (pannus formation)
What are the signs/symptoms of the chronic cicatricial phase of trachoma?
Herbert pits Arlt's line Conjunctival scarring trichiasis entropion corneal opacities
Describe the SAFE strategy for trachoma management?
Surgery for trichiasis
Antibiotics - single dose of 1000mg azithromycin
Facial cleanliness
Environmental improvement
What disease is caused by the filarial nematode Onchocerca volvulus, carried by the simulus black fly?
River blindness (onchocerciasis)
What is the colloquial name for onchocerciasis?
River blindness
What morphology of rash often appears before ocular features of river blindness?
maculopapular
What are the ocular signs of river blindness?
Decreased VA
anterior uveitis
Pearly shaped pupil (posterior synechiae)
bilateral chorioretinitis with RPE atrophy
Visualisation of nematode on slit lamp
What sorts of uveitis are associated with river blindness?
anterior and posterior
What drug is given to treat river blindness?
ivermectin
Deficiency of which vitamin results in xerophthalmia?
vitamin A
What are the features of xerophthalmia?
nyctalopia xerosis (severe conjunctival dryness and keratinization Bitot's spots Punctate corneal epithelial erosions keratomalacia
What is the treatment of xerophthalmia?
vitamin A supplementation
Topical lubricants