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Biochimie > Glicoliza > Flashcards

Glicoliza Flashcards

1
Q

Hexokinaza si glucokinaza

A

Glucoza in glucozo6fosfat

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2
Q

Fosfoglucoizomeraza

A

Glucozo6fosfat in fructozo6fosfat

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3
Q

Fosfofructokinaza1 FFK1

A

Fructozo6fosfat in fructozo1,6disfosfat

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4
Q

Triozofosfatizomeraza

A

DHAP in GA3P

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5
Q

Gliceraldehid3fosfatdehidrogenaza

A

GA3P in 1,3difosfoglicerat

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6
Q

Fosfogliceratkinaza

A

1,3difosfoglicerat in 3fosfoglicerat

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7
Q

Fosfogliceratmutaza

A

3fosfoglicerat in 2fosfoglicerat

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8
Q

Piruvatkinaza

A

Fosfoenolpiruvat in piruvat

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9
Q

Localizare hexokinaza

A

Toate celulele extrahepatice

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10
Q

Afinitatea hexokinazei pt glucoza

A

Mare

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11
Q

Afinitatea glucokinazei pt glucoza

A

Mica

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12
Q

Inhibitorul hexokinazei

A

Glucozo6fosfat

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13
Q

Inhibitorul glucokinazei

A

Doar glucagon

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14
Q

Inhibitorii FFK1

A

ATP,citrat

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15
Q

Stimuleaza FFK1

A

AMP, fructozo2,6difosfat

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16
Q

Cresterea raportului insulina/glucagon

A

Activeaza FFK2 ceea ce duce la producerea de fructozo2,6difosfat ceea ce stimuleaza FFK1

17
Q

Scaderea raportului insulina/glucagon

A

Activeaza fructozo2,6dufosfataza ceea ce duce la producerea de fructozo6fosfat deci nu exista fructozo2,6difosfat care sa stimuleze FFK1

18
Q

Inhibitorii piruvatkinazei

A

ATP,alanina,acetilcoa,AG cu lant lung, glucagon

19
Q

Activatorii piruvatkinazei

A

Fructozo1,6difosfat si insulina

20
Q

Deficit de piruvatkinaza

A

Anemie hemolitica

21
Q

Ce transforma 1,3DPG in 2,3DPG

A

Fosfogliceratmutaza

22
Q

Soarta piruvatului

A

Acetilcoa sau acid lactic sau OAA sau etanol

23
Q

Componentele PDH

A

Piruvatdecarboxilaza, dihidrolipoiltransacetilaza, dihidrolipoilhidrogenaza

24
Q

Ce catalizeaza transformarea piruvatului in acetilcoa

A

TPP,acid lipoic,HSCoA,FAD,NAD

25
Q

Activatorii PDH

A

Acetilcoa, NAD

26
Q

Inhibitorii PDH

A

Piruvat, ADP, DCA

27
Q

Piruvat in OAA

A

Enzima piruvatcarboxilaza

+biotina, Mg

28
Q

Ce influenteaza acetilcoa

A

Inhiba PDH

Stimuleaza piruvatcarboxikinaza

29
Q

Stimuleaza PEPCK

A

ATP,OAA,glucagon

30
Q

Imhibitorii fructozo1,6bifosfatazei

A

Fructozo2,6difosfat,AMP

31
Q

Stimuleaza fructozo1,6difosfataza

A

OAA,glucagon

32
Q

Stimuleaza glucozo6fosfataza

A

Glucoza mica,glucagon

Biochimie (9 decks)

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