Glia Flashcards

1
Q

are glia excitable or non excitable

A

Non excitable

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2
Q

what are the two group of glia in the cns

A

macroglia and microglia

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3
Q

what germ layer gives rise to macroglia

A

Ectoderm

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4
Q

what germ layer gives rise to microglia

A

Mesoderm

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5
Q

give two examples of macroglia

A

astrocytes and oligodendrocytes

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6
Q

what groups of glia are found in the pns

A

1) schwann cells - non-excitable, excitable
2) olfactory sheathing
3) satellite glial cells
4) enteric glia

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7
Q

where do astrocytes extend projections to

A

nodes of ranvier (axons), dendrites, neural vascular endothelium, under pia mater

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8
Q

a single astrocyte makes contact with multiple dendrites of a neuron. true or false

A

true

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9
Q

a single neuron is contacted by multiple astrocytes. true or false

A

true

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10
Q

the presence of which neuronal cell type causes an immature schwann cell to develop into a myelinating cell

A

neurons

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11
Q

can schwann cells turn into immature schwann cells after injury?

A

Yes

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12
Q

microglia are derived from what type of cells

A

foetal macrophages

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13
Q

during embryonic development, embryonic glial cells invade what structure

A

Neural tube

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14
Q

after birth, what structure in the brain do microglia precursor cells invade

A

corpus callosum

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15
Q

give to examples of neuropeptides secreted by glial cells

A

Angiotensinogen

Atrial natriuretic peptide

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16
Q

what does wiring transmission refer to in context of glia

A

wiring transmission is a form of transmission/signalling

it is:

only intracellular
between only two cells
rapid

17
Q

what is volume transmission in the context of glia

A

form of transmission/signalling

it is:

intracellular and extracellular
between more than two cells
(a signal released in one cell affects many others)
slow

18
Q

following an action potential, extra extracellular potassium is taken up by which cells

A

Astrocytes

19
Q

astrocytes have a high potassium conductance. true or false

A

True

20
Q

how is potassium taken up into astrocytes

A

1) potassium channels
2) Na/K ATPase pump
3) Na/K/2Cl exchanger

21
Q

after one astrocyte takes up extracellular potassium, the K diffuses between cells through gap junctions. true or false? what is the name of this process

A

true. spatial buffer