Glaucoma Meds 2 Flashcards

1
Q

Name 2 alpha 2 agonists

A

Apraclonidine 0.5% (iopdine)

Brimonidine 0.2% (alphagan)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Name 2 CAIz

A

Dorzolamide 2% (Trusopt)

Brinzolamide 1% (Azopt)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Ocular Side effect of cholinergic agonist

A

Brow ache

Accommodative spasm

Pupil block in advanced cataract

RD in high myopes

Sting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Systemic side effect of cholinergic agonist

A

Headache

Arrythymia

Salivation

Sweating

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Ocular contraindications for cholinergic agonist

A

High myope

Cataract

Px <40 as can’t tolerate spasm

Inflammation

Uveitic/neovascular glaucoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Systemic contraindication for cholinergic agonist

A

Asthmatics

Ulcers

Bladder dysfunction

Parkinson

Already uses systemic cholinergic agonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Ocular side effect of cholinesterase inhibitors

A

Iris cysts

Acceleration of cataract

RD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Ocular side effect of a2 agonist

A

Conjunctival blanching

Minimal mydriasis

Lid retraction and dry eye

Itch

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Systemic side effect of a2 agonist

A

Dry mouth

Fatigue

Taste abnormality

Headache

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Contraindication for a2 agonist

A

CVD

Maoi

TCA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Ocular side effect of beta blockers

A

Dry eye

Allergy

Decreased corneal sensitivity

Punctuate epithelial erosion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Systemic side effect of beta blockers

A

Impotence

Depression

Bradycardia

Bronchospasm

Hypotension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Contraindication for beta blocker

A

Narrow angles

Impotence

Depression

Nightmares

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Ocular side effect of CAI

A

Sting

Irreversible corneal decompensation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Systemic side effect of CAI

A

Bitter taste

Headache

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Contraindication for CAI

A

Corneal endothelial compromise

Hypersensitivity to sulphonamides

17
Q

Side effect of CAi (acetazolamide version)

A

Anorexia

Parses thesis of hands/feet

Aplastic anaemia and Steven Johnson

Renal stones

18
Q

Contraindication of CAI

Acetazolamide version

A

Hypersensitivity to sulphonamides

Renal problems

Pregnancy

19
Q

Side effect of prostaglandin analogues

A

Periorbiral pigment

Increase lash thickness and length

Deactivation of AU and herpes

CMO

20
Q

Contraindication for Prostagalndin analogues

A

Inflammmatory disease

CMO

HSV KERATITIS

Pregnancy

21
Q

Why is mono therapy preferred

A

Convenient

Less likely for mistakes

Less drug interactions

Less preservative so less toxicity to cornea

22
Q

How do prostaglandin analogues work

A

Bind to prostanoid FP receptor in CB

Increase MMP

relax ciliary muscle and remodel ECM of ciliary muscle

Increase uveoscleral outflow

23
Q

Systemic side effect of prostaglandin analogues

A

Headache

Respiratory problems

24
Q

Name non selective beta blockers

A

Timolol 0.25/0.5 (timoptic)

Carteolol 1%

Metipranolol 0.3 (optipranolol)

Levobunolol 0.25 (Betagan)

25
Q

Name the B1 selective Beta blocker

A

Betaxolol 0.25/0.5 (Betoptic)

26
Q

Why is betaxolol good and bad

A

Selective for B1 so less risk to asthmatics but less IOP decrease than timolol