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Pharma > Glaucoma Drugs > Flashcards

Glaucoma Drugs Flashcards

1
Q

Netarsudil MOA?

A

Rho kinase inhibitor

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2
Q

Netarsudil s/e?

A

Deposit over cornea - cornea verticillata

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3
Q

Ace i metabolism by?

A

Kidney

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4
Q

Ace i metabolized by liver

A

Fosinopril and moxepril

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5
Q

Lipid soluble beta blockers

A

LMP
LABETOLOL
METAPROLO
PROPRANOLOL

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6
Q

T type CCB receptors present in?

A

Nerves

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7
Q

Non specific CCB?

A

Verapamil

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8
Q

Anal fissures which ointment is used?

A

Verapamil+ligno
Diltiazem
NTG

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9
Q

Diltiazem s/e?

A

Gum hypertrophy
Heart block
Constipation
Headache

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10
Q

Doc for htn crisis
Mxtx of htn
Vasospastic angina

A

Dihydropyridine

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11
Q

Doc for sub arachnoid hemorrhage

A

Dihydropyridine

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12
Q

Captopril fast or slow action?

A

Fast.

Capto and lisinopril are fast action drugs

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13
Q

Beta blockers with lipid solubility?

A

LMP
LABETOLOL
METAPROLOL
Propanol

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14
Q

Non lipid soluble/kidney elimination beta blockers?

A

ANS
atenolol
Nadolol
Sotalol

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15
Q

Nifedipin s/e

A

Gum hypertrophy

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16
Q

sodium nitroprusside acts on?

A

both arterioles and venules

17
Q

sodium nitroprusside s/e?

A

cyanhemoglobin, NaI blockade=hypothyroidism

18
Q

hypertensive emergency?

A

more than 180/110 with end organ damage

19
Q

Nitric oxide iducer CCB?

A

hydralazine

20
Q

NTG acts on?

A

Venodialtor>arterio (MOA: venous pooling- reduced return- reduced preload and stretching

21
Q

dose of ntg?

A

0.3 to 0.6mg sublingual

22
Q

steal phenomena?

A

Dipyridamole and isoflurane

23
Q

robinhood phenomena?

A

Beta blockers and Nitroglycerines (TIP: roBiNhood)

24
Q

to prevent tolerance for NTG what should be done?

A

8-10 hours gap- NITRATE FREE PERIOD

25
Q

Telmisartan special use?

A

in DM, to prevent renal scarring/sclerosis

26
Q

Losartan (ARB) action on plt and uric acid?

A

anticoag and uricosuric

27
Q

HTN crisis DOC?

A

NICARDIPIN

28
Q

all nitrates have high 1st pass met, hence not given orally. But, which nitrate is given orally only?

A

isosorbide mononitrate

29
Q

DOC for nitrate poisoning?

A

methylene blue

30
Q

trimetazidine moa?

A

pFOX inhibitor - partial fatty acid oxidn

31
Q

Morphine indicated in which cardiac condition?

A

2nd doc in pulm edema after furesemide

32
Q

name some inodilators and its indications?

A

Amrinone, milri, levosimendon. Inotropic action and dialtor action. Thus, used in CHF e pulm htn.

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