Glaucoma drugs

Question 1

What are the prostaglandin analogues

Answer 1

Dose: qhs

1. latanaprost (Xalatan)
2. Travaprost (Travatan)
3. Brimatoprost (Lumigan)
4. Tafluprost (Zioptan)

Question 2

What is the MOA of prostaglandins

Answer 2

increases the aqueous outflow through the uveoscleral

Question 3

What are the indications of prostaglandins

Answer 3

1. poag
2. ntg
3. pds
4. exfoliation syndrome

Question 4

what are contraindications of prostaglandins

Answer 4

pregnant/nursing moms, and ocular inflammation

Question 5

what are the beta blockers

Answer 5

Dose: BID
can mask symptoms of hypoglycemia
1. Timolol (betimol, timoptic)
2. Istalol
3. Betaxolol (Betoptic)
4. carteolol
5. levobunolol (Betagan)
6. metipranolol (OptiPranolol)

Question 6

what are the alpha 2 agonists

Answer 6

Dose: TID
Don't use with patients who take antidepressants
1. apraclonidine (Iopidine)
2. brimonidine (Alphagan)
3. depivefrin (propine)

Question 7

what are the carbonic anhydrase inhibitors

Answer 7

Dose: BID and TID
Caution with sulfa allergies, diabetic patients with ketoacidoses, hepatic ind's and COPD
1. acetazolamide (oral) (Diamox)
2. methazolamide (oral 150 mg max dose)
3. dorzolamide (Trusopt)
4. brinzolamide (Azopt)

Question 8

what are the cholinergics

Answer 8

Dose: qid
Miotic- contains BAK and EDTA
1. carbachol (isopto carbachol)
2. pilocarpine (Isopto carpine)

Question 9

what are the osmotics

Answer 9

1. glycerin
2. isosorbide (DM patients)
3. mannitol (iv)
4. urea (iv)