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OCULAR PHARM FINAL > GLAUCOMA > Flashcards

GLAUCOMA Flashcards

1
Q

Trusopt AKA

A

Dorzolamide

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2
Q

Diamox AKA

A

Acetazolamide

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3
Q

CI for beta blockers

A

Heart + lung problems

  • raynauds
  • pregnancy
  • Myesthenia gravis
  • hypotension
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4
Q

Vyzulva AKA, MOA

A

Latanoprostene bunod
Bisarta
Prostaglandin-> it increases US outflow by donating NO in the smooth TM muscle
Activates cGMP signaling

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5
Q

Glaucoma drug most likely to cause allergy

A

Apraclonidine -Iopidine (alpha 2 agonist)

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6
Q

Main side effects of CAIs

A 
Bitter taste
Stinging 
Hyperemia 
Corneal endothelium 
Aplastic anemia 
Bone marrow 
Kidney stones 
Electrolyte 
Metabolic acidosis 
Paresthesia
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7
Q

Drug that doesn’t decrease AH production

A

Pilocarpine

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8
Q

Side effects of Beta blocker

A 
Bradycardia 
Bronchoconstriction 
Corneal hypoesthesia 
Low BP 
Tachyphylaxis
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9
Q

POAG patient who is allergic to BAK what do you use?

A

Zioptan/ tafluprost
Tavatan/travoprost
Xelpros

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10
Q

Med not used w herpes

A

Prostaglandins

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11
Q

Prostaglandins drug causes lash growth

A

Bimatoprost/ Lumigan

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12
Q

Xalatan AKA has to be used cautiously on pts w the following

A 
Latanoprost 
Iritis- inflammation 
ME 
Aphakia, torn lens capsule 
HSK 
Renal/ hepatic problems
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13
Q

Pt having angle closure attack, whats a poor treatment choice

A

Acetazolamide

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14
Q

Prostaglandin ocular side effects

A

Droopy eyelids, sunken eyes, itching, pigmentation changes, lash growth

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15
Q

Alpha agonist ocular side effects

A

Allergy, burning, allergic conjunctivitis, blurring, HA

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16
Q

CAIs ocular side effects

A

Stinging, eye discomfort, bad taste, hyperemia

17
Q

RhoKinase inhibitor ocular SE

A

Eye redness, corneal deposits sting, small bleeds on white eye

18
Q

Pilocarpine ocular SEs

A

Browache, miosis, angle closure, RD

19
Q

Alpha agonist systemic SEs

A

Fatigue, HA, drowsiness, dry mouth/ nose , allergies

20
Q

Alpha agonist systemic SE in kids

A

Coma

21
Q

CAIs systemic side effects

A

Tingling hands/feet, fatigue, stomach upset, memory problems, urination, acidosis

22
Q

Pilocarpine systemic SEs

A

Dumbells

23
Q

Apraclonidine

A

Allergies

24
Q

Drugs that are bad for Fuchs

A

CAIs and alphagan

25
Q

Ester linkages

A

Shorter duration of action and localized

Anesthetics

26
Q

Indomethacin

A

Whorl corneal opacities

27
Q

Flomax AKA

A

Tamulosin

28
Q

NOT a common side effect of anti-VEGF

A 
Blurred vision 
Scratchy sensation 
RD 
Subconjunctival hemorrhage 
New floaters 
Hemes 
Infection
29
Q

Mast cell stab names

A

Cromolyn (crolom)

Lodoxamide (alarmast) and nedocromil (alocril)

30
Q

Topical anesthetic injectable are used w epinephrine

A

To increase duration by preventing systemic absorption and decrease bleeding

31
Q

Not an adverse effect of antihistamines

A

Diarrhea

32
Q

Not an alpha agonist thats used as a decongestant

A

Diphenhydramine

Benadryl

33
Q

TM outflow SOA

A

Adenosine a1 agonist
RhoKinase inhibitors+ Norepinephrine
M3agonist (pilocarpine)

34
Q

US pathway SOA

A

Prostaglandins

A2 agonist

35
Q

AH inflow SOA

A 
BB 
A2 agonist 
CAIs 
RhoKinase 
Trabedenoson (a1)
36
Q

Drugs that decrease AH production

A

Timolol, Betaxolol, levobunolol, cartelol (Topical Beta bLoCkers)

Apraclonidine, Brimonidine (alpha 2 selective)
Acetalazolamide, brinzolamide, dorzolamide ( CAIs)

37
Q

Drugs that increase US outflow

A

Prostaglandins

Latanoprost, Brimatoprost, tafluprost

38
Q

Increase TM outflow

A

Non selective alpha agonist - phrine

Cholinomimetic drugs - pilocarpine, physostigmine, Echothiophate

OCULAR PHARM FINAL (1 decks)

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