GLAUCOMA Flashcards
Trusopt AKA
Dorzolamide
Diamox AKA
Acetazolamide
CI for beta blockers
Heart + lung problems
- raynauds
- pregnancy
- Myesthenia gravis
- hypotension
Vyzulva AKA, MOA
Latanoprostene bunod
Bisarta
Prostaglandin-> it increases US outflow by donating NO in the smooth TM muscle
Activates cGMP signaling
Glaucoma drug most likely to cause allergy
Apraclonidine -Iopidine (alpha 2 agonist)
Main side effects of CAIs
Bitter taste Stinging Hyperemia Corneal endothelium Aplastic anemia Bone marrow Kidney stones Electrolyte Metabolic acidosis Paresthesia
Drug that doesn’t decrease AH production
Pilocarpine
Side effects of Beta blocker
Bradycardia Bronchoconstriction Corneal hypoesthesia Low BP Tachyphylaxis
POAG patient who is allergic to BAK what do you use?
Zioptan/ tafluprost
Tavatan/travoprost
Xelpros
Med not used w herpes
Prostaglandins
Prostaglandins drug causes lash growth
Bimatoprost/ Lumigan
Xalatan AKA has to be used cautiously on pts w the following
Latanoprost Iritis- inflammation ME Aphakia, torn lens capsule HSK Renal/ hepatic problems
Pt having angle closure attack, whats a poor treatment choice
Acetazolamide
Prostaglandin ocular side effects
Droopy eyelids, sunken eyes, itching, pigmentation changes, lash growth
Alpha agonist ocular side effects
Allergy, burning, allergic conjunctivitis, blurring, HA
CAIs ocular side effects
Stinging, eye discomfort, bad taste, hyperemia
RhoKinase inhibitor ocular SE
Eye redness, corneal deposits sting, small bleeds on white eye
Pilocarpine ocular SEs
Browache, miosis, angle closure, RD
Alpha agonist systemic SEs
Fatigue, HA, drowsiness, dry mouth/ nose , allergies
Alpha agonist systemic SE in kids
Coma
CAIs systemic side effects
Tingling hands/feet, fatigue, stomach upset, memory problems, urination, acidosis
Pilocarpine systemic SEs
Dumbells
Apraclonidine
Allergies
Drugs that are bad for Fuchs
CAIs and alphagan
Ester linkages
Shorter duration of action and localized
Anesthetics
Indomethacin
Whorl corneal opacities
Flomax AKA
Tamulosin
NOT a common side effect of anti-VEGF
Blurred vision Scratchy sensation RD Subconjunctival hemorrhage New floaters Hemes Infection
Mast cell stab names
Cromolyn (crolom)
Lodoxamide (alarmast) and nedocromil (alocril)
Topical anesthetic injectable are used w epinephrine
To increase duration by preventing systemic absorption and decrease bleeding
Not an adverse effect of antihistamines
Diarrhea
Not an alpha agonist thats used as a decongestant
Diphenhydramine
Benadryl
TM outflow SOA
Adenosine a1 agonist
RhoKinase inhibitors+ Norepinephrine
M3agonist (pilocarpine)
US pathway SOA
Prostaglandins
A2 agonist
AH inflow SOA
BB A2 agonist CAIs RhoKinase Trabedenoson (a1)
Drugs that decrease AH production
Timolol, Betaxolol, levobunolol, cartelol (Topical Beta bLoCkers)
Apraclonidine, Brimonidine (alpha 2 selective)
Acetalazolamide, brinzolamide, dorzolamide ( CAIs)
Drugs that increase US outflow
Prostaglandins
Latanoprost, Brimatoprost, tafluprost
Increase TM outflow
Non selective alpha agonist - phrine
Cholinomimetic drugs - pilocarpine, physostigmine, Echothiophate