Glaucoma 1 Flashcards
If PAS is seen to extend anterior to the schwalbe line what condition should you suspect?
ICE syndrome
Preperimetric glaucoma
Glaucomatous changes in optic discs with normal visual fields
What portion of the TM has the most resistance to outflow?
juxtacanalicular TM (inner most that is adjacent to the Schlemn canal)
What is thought to be the age range for Juvinille open angle glaucoma (JOAG)?
4-35 yrs
Risk factors for open angle glaucoma
- IOP * Age * AA * Family Hx * CCT * Female * CRVO * ?? HTN, DM, Myopia, Hypothyroidism, ??
Risk Factors for closed-angle glaucoma
- Race (Inuits, Asian) * Female * Hyperopia (far sightedness) * Family history * Advanced age > 50
How many cililiary processes are there?
About 80
What is the arterial source for the ciliary processes?
branches of the major arterial circle of the iris
Aqueous humor is produced what what three mechanisms? What is the major contributing mechanism?
- ACTIVE TRANSPORT * Ultrafiltration * simple diffusion
What ions in the aquous humor are in excess compared to plasma? Lower?
- Chloride, H+, Vit C * Bicarbonate
What are the three major types of aqueous suppresants?
- Beta blockers * Alpha 2 agonists * Carbonic anhydrase II inhibitors
What is the rate of aqueous turnover?
1% per min equaling full turnover every 1-2 hours
What is the pressure-independent aqueous outflow pathway?
uveoscleral pathway making up approx 10% of total outflow
What is normal diurnal variation and what would be suggestive of glaucoma?
2-6mmMg >10mmMg diurnal variation
What is a promising type of tonometry that is challenging goldmann tonometry?
Dynamic contour tonometry? (DCT)
What is the average rate of aqueous production?
2.0-2.5 ul/min
What is the method used to measure the rate of aqueous formation?
fluorophotometry
What is the method used to measure the rate of aqueous out-flow?
tonography
What is the normal variation in superior versus inferior visual fields?
Superior field in normally depressed 1-2 dB
What does a “cloverleaf” visual field suggest?
The patient stopped participating part way the the exam