GIT Surgery Flashcards
State an examples of prokinetic agents
Metoclopramide
Domeperidone
Erythromycin
Mucosal protection agents such as …………… help to protect against other non-acidic agents in the refluxate however it can cause……………….
-Sucralfate
-unpleasant taste and constipation
Causes of functional obstruction
- vascular occlusion ileus: acute or chronic ischemia
- Adynamic or inhibition:
*Post operative paralytic ileus (most *common)
*Metabolic causes (DKA, hyponatremia, hypokalemia, hypomagnesaemia)
*Drugs (morphine, TCA, antacid, anticonvulsants)
*intra abdominal inflammation
*sepsis or occult wound infection
*pneumonia
*renal stones
*retroperitoneal hematoma
*fracture spine and ribs - spastic ileus: (intestine remains contracted not propulsive)
*mesentric vascular occlusion (MVO)
*pseudo-obstruction
*uremia
*prophyria
*heavy metal poison
Treatment of recurrent adhesive intestinal obstruction
-Repeat adhesiolysis alone (open/laproscopic)
-adhesiolysis with seprafilm(decrease fibrin formation)
-noble’s intestinal plication
-child phillips transmesenteric plication
-baker intestinal intubation
Causes of paralytic ileus
-post operative
-infection:
Intra abdominal sepsis
Abscess
Peritonitis
-reflex ileus:
Following fractures of the spine or ribs
Retroperitoneal hemorrhage
-metabolic:
Uremia
Hypokalemia
Hypothyroidism
-medications:
Anticholinergics
Opiates
Calcium channel blockers
The teat of choice in paralytic ileus is ………..
CT scan
Treatment of ogilvie syndrome
Colonic decompression
Neostigmine
………….. is the most common neoplasm of the small intestine
Adenoma
…………… is the treatment of choice for tubular adenoma and brunner’s gland hyperplasia
Endoscopic polypectomy
Common primary malignancies that can give small intestinal metastasis includes…………….
Malignant melanoma (the most common)
Ovarian cancer
Bladder cancer
Breast cancer
Lung cancer
Gardner’s syndrome is a triad of ……….
Gastrointestinal polyps
Skin and soft tissue tumors
Multiple osteoma
Carcinoid tumors arise from………..
Kulchitsky cells in the crypts of lieberkuhn (ECL cells)
Neuroendocrine cells (APUD system)
Causes of diffuse (generalized) abdominal pain
Gut perforation
Mesenteric ischemia
AAA
acute pancreatitis
DM
Pharyngeoesophageal ligament is an extension of …………
The inferior diaphragmatic fascia
The left gastric artery is from ………..
Coeliac artery
Pyrosis is ………..
Heartburn
Barrett’s esophagus is ……….. above GEJ
2 cm
…………. Is the gold standard of quantifying the degree of reflux
Ambulatory 24 hours pH monitoring
Esomeprazole is the ……………
S-isomer of omeperazole
………….. surgery is used in patients in whom the GEJ can’t be reduced below the diaphragm
Collis-gastroplasty
Endoscopic GERD therapy
-radiofrequency energy deliveredto the LES (Stretta procedure)
-suture ligation of the cardia (Endoscopic plication “bard Endo Cinch”)
-submucosal implantation of inert material in the region of the LES (Enteryx)
-Linx system
What are the ulcerogenic drugs which inhibit synthesis of protective PG
NSAIDs
Corticosteroids
Erythromycin
Iron
KCL
Cyclophosphamide
Methotrexate
Azathioprine
What can cause hourglass stomach
Long standing gastric ulcer
What is moynhan’s sign?
It’s perforation of peptic ulcer with pain in the right iliac fossa because fluid may track along the right paracolic gutter to the right iliac fossa causing pain in the right iliac fossa