GIT (exam 4) Flashcards
PNS is excitatory or inhibitory on the GIT?
excitatory
SNS is excitatory or inhibitory on the GIT?
inhibitory
Enteric system falls under what organization of the nervous system?
autonomic nervous system
Intrinsic Innervation (enteric nervous system) : Myenteric plexus (Auerbach’s plexus) controls?
Motility
think M and M for Myenteric and Motility
Intrinsic Innervation (enteric nervous system) : Submucosal plexus ( Meissner’s plexus) controls?
Secretion and blood flow
think S and S for submucosal and secretions
what are the four “official” GI hormones?
gastrin
cholecystokinin
secretin
GIP
When is gastrin released?
in response to a meal
Upon stimulation gastrin causes what two reactions to take place?
Increases H+ secretion by gastric parietal cells
Stimulates growth of gastric mucosa – trophic action.
Stimuli for gastrin secretion?
Secreted from G cells of the gastric antrum
Gastrin is secreted from G cells of the gastric antrum in response to what three factors?
Small peptides and amino acids esp. phenylalanine and tryptophan (proteins)
Distension of stomach
Vagal stimulation
What causes inhibition of Gastrin secretion?
Acid (hydrogen) in the lumen of the stomach inhibits gastrin release via negative feedback.
Explain gastrin release and how the release is stopped?
gastrin is released in response to a meal, which increases H+ secretion in the stomach, the increase in acid creates neg. feedback to inhibit gastrin release.