Gingiva

Question 1

What is efferent nerve supply for the oral mucosa?

Answer 1

mostly sympathetic autonomic (for blood vessels)

Question 2

What is afferent nerve supply in gingiva?

Answer 2

from 2nd and 3rd divisions of trigeminal nerve

Question 3

what is the subepithelial plexus network in the reticular layer of the lamina propria?

Answer 3

it is a bunch of unmyelinated nerves in the lamina propria

Question 4

what are free nerve endings usually associated with in the epithelium?

Answer 4

Merkels cells

Question 5

what are free nerve endings associated with in lamina propria?

Answer 5

Schwann Cells, they have nociceptor, mechanoreceptor, and thermoreceptor function

Question 6

Organized nerve endings are classified as group of nerve fibers surrounded by connective tissue capsule, they enclude, meissners, ruffini and Karause’s bulbs. Where are they found and not found?

Answer 6

Not in epithelium, rather they are in lamina propria, esp in maxillary anterior

Question 7

does the circular group attach directly to tooth?

Answer 7

no

Question 8

What is vimentin?

Answer 8

an intermediate filament protein in cells of mesenchymal origin

Question 9

what is desmin?

Answer 9

an intermediate filament protein in muscle cells

Question 10

what are keratins?

Answer 10

an intermediate filament protein in epithelial cells and their derivatives

Question 11

What are adherens junctions(cell cell) made of?

Answer 11

Cadherin as transmembrane protein, cadherin from other cell as extracellular ligand, actin filaments as intracellular cytoskeletal attachment, and alpha and beta catenins as intracellular anchor proteins

Question 12

what are desmosomes(cell cell) made of?

Answer 12

cadherin, desmogleins of neighboring cells, intermediate filaments, and desmoplakins

Question 13

what are focal adhesions (cell matrix) made of?

Answer 13

integrins, ecm proteins, actin filaments, talin vinculin alpha actin filamin

Question 14

what are hemidesmosomes (Cell matrix) made of?

Answer 14

integrin a6b4, ecm proteins, intermediate filaments, plectin BP230

Question 15

What are langerhan’s cells?

Answer 15

immmune cells only found in epithelium. They are macrophage like and characterized by intracellular Birbeck granules

Question 16

What are merkel cells and where are they?

Answer 16

they are sensory cells associated with nerve fibers that extend into the epithelium. They are only found in the epithelium

Question 17

what is Filaggrin and where is it found?

Answer 17

it is a keratin associated protein found in keratohyalin graules in the upper part of the granular cell layer. It helps organize keratin as cell migrates from basal layer to outer layer to become flat and anucleated

Question 18

What do fibroblasts do?

Answer 18

they are responsible for the synthesis and degradation of eCM and collagen synthesis cascade

Question 19

what is laminin?

Answer 19

an adhesive glycoprotein of basement membrane