Giardia lambilia Flashcards

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1
Q

Giardia lambilia (other names)

A

Giardia intestinal - Giardia duodenalis

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2
Q

General info about Giardia lamblia

A
  • First protozoan parasite described

- The most common protozoal intestinal parasite

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3
Q

distribution

A

In both temperate and tropical regions

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4
Q

High risks for whom??

A

Travelers and immunocompromised patients

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5
Q

Habitat for Giardia ?

A

Duodenum, jejunum and upper ileum

- may present in gall bladder and billary passages

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6
Q

stages of Giardia lambila ?

A
  • Trophozoite( pathogenic)

- cyst( infective)

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7
Q

morphology of trophozoite

A
  • Pear shaped
  • Bilateral symmetrical
  • Bilobed adhesive disk with 2nuclei and Central large karyosome
  • four pairs of flagella
  • two axonemes
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8
Q

morphology of cyst

A
  • ovoid has 4 nuclei
  • axonemes
  • double wall
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9
Q

Definitive host

A

Human

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10
Q

mode of infection

A

Feco-oral

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11
Q

excystation site

A

Stomach and duodenum

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12
Q

encysration site?

A

Colon

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13
Q

Pathogenesis of Giardia

A
  • atrophy of intestinal villi
  • lactase deficiency
  • malabsorption syndrome
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14
Q

Risk factors for Giardia

A
  • Acholorhdia
  • CHO rich diet
  • Bacterial colonization of intestine
  • malnutrition
  • hypogammaglobulinemia
  • IgA deficiency
  • chronic pancreatitis
  • children with A blood group
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15
Q

Diagnosis of Giardia lamblia

A

Stool examination
String test
Duodenal aspiration
Serodiagnosis

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16
Q

Treatment of Giardia lamblia

A

Metronidazole (Flagyl)