Giardia lambilia Flashcards
Giardia lambilia (other names)
Giardia intestinal - Giardia duodenalis
General info about Giardia lamblia
- First protozoan parasite described
- The most common protozoal intestinal parasite
distribution
In both temperate and tropical regions
High risks for whom??
Travelers and immunocompromised patients
Habitat for Giardia ?
Duodenum, jejunum and upper ileum
- may present in gall bladder and billary passages
stages of Giardia lambila ?
- Trophozoite( pathogenic)
- cyst( infective)
morphology of trophozoite
- Pear shaped
- Bilateral symmetrical
- Bilobed adhesive disk with 2nuclei and Central large karyosome
- four pairs of flagella
- two axonemes
morphology of cyst
- ovoid has 4 nuclei
- axonemes
- double wall
Definitive host
Human
mode of infection
Feco-oral
excystation site
Stomach and duodenum
encysration site?
Colon
Pathogenesis of Giardia
- atrophy of intestinal villi
- lactase deficiency
- malabsorption syndrome
Risk factors for Giardia
- Acholorhdia
- CHO rich diet
- Bacterial colonization of intestine
- malnutrition
- hypogammaglobulinemia
- IgA deficiency
- chronic pancreatitis
- children with A blood group
Diagnosis of Giardia lamblia
Stool examination
String test
Duodenal aspiration
Serodiagnosis