GI - Upper GI Bleed, Small Bowel Obstruction, Large Bowel Obstruction, Pseudo-obstruction, Diverticular Disease and Diverticulitis, Gastritis Flashcards

1
Q

Upper GI bleed - where is the bleed from?

A

Oesophagus

Stomach

Duodenum

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2
Q

Upper GI bleed - what defines an upper GI bleed from a lower GI bleed?

A

Defined as an UGIB if bleeding is from a source proximal to the LIGAMENT of TREITZ

Ligament of Treitz is a suspensory ligament of the duodenum, and marks the boundary between the upper and lower GI tract

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3
Q

Upper GI bleed - what are some causes?

A
  1. Oesophageal varices
  2. Mallory-Weiss tear - tear of oesophageal mucous membrane
  3. Ulcers or stomach or duodenum
  4. Cancers of stomach or duodenum
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4
Q

Upper GI bleed - what is the common presentation?

A
  1. Haematemesis - ‘COFFEE GROUND’ vomit, caused by digested blood
  2. Melaena - tar like, black, greasy, digested blood
  3. Haemodynamic instability due to blood loss so:
    hypotensive
    tachycardic
    other shock signs
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5
Q

Upper GI bleed - what is the scoring system used on initial presentation, and what is taken into account?

A

Glasgow-Blatchford Score

Establishes risk of having upper GI bleed

Score>0 high risk of UGIB

Features taken into account:
Decreased Hb
INCREASED UREA
BP
HR
Melaena
Syncope
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6
Q

Upper GI bleed - why does urea increase?

A

Blood in GI tract broken down by acid and digestive enzymes, and one of the breakdown products is urea, which is then absorbed in the intestines

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7
Q

Upper GI bleed - what is the rockall scoring?

A

Comprised of both a pre and post endoscopy score - added together for overall value

Pre-endoscopy score:
Age 0-2
Shock 0-2
Co-morbidity 0-3

Comprised of two sections:

Post endoscopy score:
Section1,
Diagnosis 0-2
Bleeding 0-2

Section 2,
A - Age
B - BP
C - Comorbidity
D - Diagnosis
E - Endoscopic Findings
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8
Q

Upper GI bleed - what is the main diagnostic and therapeutic investigation?

A

Upper GI endoscopy

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9
Q

Upper GI bleed - what are the other bedside, bloods, and imaging you can do?

A

Bedside:
Obs
ECG
Monitor urine output

Bloods:
FBC
U&E
LFTs
VBG/ABG
Group and save with cross match

Imaging:
Chest X-ray - look for oesophageal perforation, aspiration, free air under diaphragm

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10
Q

Upper GI bleed - what do ‘group and save’ and ‘crossmatch’ mean?

A

Group and save - lab checks patient blood group, keeps sample in case need to match blood to it

Crossmatch - lab finds blood, tests it is compatible, kept in fridge to be used if necessary

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11
Q

Upper GI bleed - what is the management?

A

ABATED

A - ABCDE resuscitation

B - Bloods (FBC for Hb, U&E for urea)

A - Access, cannulas

T - Transfuse

E - Endoscopy

D - Drugs (stop anticoagulants and NSAIDs)

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12
Q

Small Bowel Obstruction - what is it?

A

The passage of food, fluids and gas through small intestines becomes blocked

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13
Q

Small Bowel Obstruction - what are the causes?

A

Adhesions - following surgery (most common cause)

Hernias

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14
Q

Small Bowel Obstruction -what are the clinical features?

A

Diffuse, central abdo pain, can be colicky

N+V - typically bilious vomiting

Constipation

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15
Q

Small Bowel Obstruction - what are the findings on examination?

A

‘Tinkling’ bowel sounds

Abdo distension

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16
Q

Small Bowel Obstruction - what are the investigations to do?

A

Abdo XRAY - generally 1st line

CT - definitive investigation, more sensitive

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17
Q

Small Bowel Obstruction - what do you see on abdo XRAY?

A

Distended small bowel loops with fluid levels

Dilated if small bowel > 3cm in diameter

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18
Q

Small Bowel Obstruction - what is the management?

A

Initially:

  • NBM
  • IV fluids
  • NG tube with free drainage

Some patients settle with conservative management, but otherwise will require surgery

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19
Q

Large Bowel Obstruction - what is it?

A

The passage of food, fluids and gas, through large intestines become blocked

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20
Q

Large Bowel Obstruction - what are the causes?

A

Tumour - colon carcinoma

Volvulus

Diverticular disease

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21
Q

Large Bowel Obstruction - what are the clinical features?

A

Abdo pain, colicky

Absence of flatus or stools

N+V

22
Q

Large Bowel Obstruction - what are the investigations?

A

Abdo XRAY - usually 1st line

CT - high sensitivity and specificity

23
Q

Large Bowel Obstruction - what do you see on an abdo XRAY, and what are the diagnostic diameter parameters?

A
  1. Dilatation:
    - Caecum 10-12cm
    - Ascending colon 8cm
    - Recto-sigmoid 6.5cm

Diameters greater than these is diagnostic for obstruction

  1. Presence of free intra-peritoneal gas indicates colonic perforation
24
Q

Large Bowel Obstruction - what is the initial management and perforation management?

A

Initial steps:

  • NBM
  • IV fluids
  • NG tube with free drainage
  • if cause does not require surgery, trial conservative Rx for 72 hours, if no resolution, further management required

If perforation suspected:
Emergency surgery
IV antibiotics

25
Q

SBO and LBO - which occurs first in which obstruction:
Vomiting?
Constipation

A

Vomiting - occurs earlier in small bowel obstruction

Constipation - occurs earlier in large bowel obstruction

26
Q

Pseudo-obstruction - what is it?

A

Condition where intestinal dilatation and symptoms resemble an obstruction, but on examination there is no obstruction

27
Q

Pseudo-obstruction - what is the pathophysiology behind it?

A

Mechanism unknown, but thought to be due to an interruption of the autonomic nerve supply to the colon, resulting in absence of smooth muscle action in bowel wall

28
Q

Pseudo-obstruction - what are some causes?

A

Electrolyte imbalance - hypercalcaemia

Meds - opioids, CCBs, anti-depressants

Recent surgery

Neurological disease - Hirschsprung’s disease, Parkinson’s, MS

29
Q

Pseudo-obstruction - what are the clinical features?

A

Most patient’s present with the clinical features of SBO and LBO:

Abdo pain
Abdo distension
Constipation
N+V - later feature

30
Q

Pseudo-obstruction - what are the investigations?

A

Bloods:
U&Es - check for electrolyte disturbances

Abdo XRAY

Abdo CT with contrast

31
Q

Pseudo-obstruction - what is the management?

A
  • NBM
  • IV fluids
  • NG tube inserted to aid decompression
  • If not resolved in 24-48h, then endoscopic decompression

Surgery

32
Q

Diverticular Disease - what is a diverticulum?

A

Outpouching of gut wall

33
Q

Diverticular Disease - where is the usual site of diverticula?

A

Usual site is between the taenia coli, where vessels pierce the muscle to supply the mucosa

34
Q

Diverticular Disease - what is diverticulosis?

A

Diverticulosis is just the presence of diverticula

35
Q

Diverticular Disease - when would you use ‘Diverticular Disease’, instead of diverticulosis?

A

Diverticular disease is reserved for when patients with diverticula become symptomatic

36
Q

Diverticular Disease - what is Diverticulitis?

A

Is when one or a few of the diverticula become infected and inflamed

37
Q

Diverticular Disease - what part of the large intestine are diverticula most common?

A

Sigmoid colon

38
Q

Diverticular Disease - what are symptoms for diverticular disease?

A

Abdo pain

Altered bowel habit

Bleeding

39
Q

Diverticular Disease - how is it diagnosed?

A

Commonly diagnosed as an incidental finding

Barium enema

40
Q

Diverticular Disease - what is the main cause?

A

Low-fibre western diet, which leads to high intraluminal pressure that forces mucosa to herniate through muscle layers of the gut

41
Q

Diverticular Disease - what is the treatment?

A

Increase dietary fibre intake

Antispasmodics - Mebeverine

42
Q

Diverticulitis - what are the risk factors?

A

Age

Lack of dietary fibre

Obesity

Smoking

NSAID use

43
Q

Diverticulitis - what are the symptoms?

A

Acute diverticulitis typically presents:

  • LIF severe pain
  • N+V
  • change in bowel habit, constipation (50%), diarrhoea (25%)
  • Urinary frequency, urgency, dysuria, due to irritation of the bladder by the inflamed bowel
44
Q

Diverticulitis - what are the signs?

A

Tender LIF

Pyrexia

Tachycardia

45
Q

Diverticulitis - what investigations can you do?

A

FBC - raised WCC
CRP - raised

Chest XRAY - may show pneumoperitoneum in cases of perforation
Abdo XRAY
CT

46
Q

Diverticulitis - what is the management?

A

Mild cases:

  • Oral antibiotics
  • Liquid diet
  • Analgesia

If symptoms don’t settle within 72 hours, admit for IV antibiotics

47
Q

Diverticulitis - what are the complications?

A

Perforation and development of abscess

Perforation and development of faecal peritonitis

Development of fistula

48
Q

Gastritis - what is it?

A

It is inflammation of the gastric mucosa (lining of the stomach)

49
Q

Gastritis - what are the causes?

A

MOST COMMON - H. Pylori

NSAIDs

Alcohol

Autoimmune gastritis

50
Q

Gastritis - what are the symptoms?

A

Most people with gastritis are asymptomatic

If symptoms are present:

  • Indigestion
  • Epigastric pain
  • N+V
  • Bloating
  • LoA
51
Q

Gastritis - what are the investigations?

A

Usually incidental finding at endoscopy (where a biopsy is taken)

Breath test for H.Pylori

Barium swallow

52
Q

Gastritis - what is the management?

A

Lifestyle:

  • Smaller meals
  • Avoid irritant foods
  • Avoid alcohol
  • Smoking cessation

Meds:

  1. Antacids
  2. H2 blocker, Ranitidine
  3. PPI
  4. Bismuth subcitrate - use it in combintion with antibiotics + PPI for H. Pylori infections